| Literature DB >> 27525443 |
Abstract
Biologic therapies for psoriasis are associated with loss of response over time. Immunogenicity, suboptimal dosing, low serum drug levels, and intermittent or episodic therapy have been documented as explanations for this phenomenon. Use of an immunomodulatory agent can reduce the risk of immunogenicity and improve clinical response. 2016 published by Frontline Medical Communications.Entities:
Keywords: Anti-drug antibodies; biologics;; immunogenicity;; loss ofzzm321990response; psoriasis; serum drug levels
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Year: 2016 PMID： 27525443 DOI： 10.12788/j.sder.2016.022
Source DB: PubMed Journal: Semin Cutan Med Surg ISSN： 1085-5629