Literature DB >> 27524854

'I'm still a hustler': entrepreneurial responses to precarity by participants in phase I clinical trials.

Torin Monahan1, Jill A Fisher2.   

Abstract

This paper questions the implications of entrepreneurial responses to conditions of employment precarity by 'healthy volunteers' in phase I clinical trials in the United States. Such individuals are typically serial participants who often identify as professional volunteers and seek out drug studies as their primary source of income. Drawing on extensive qualitative research, this paper illustrates how healthy volunteers selectively import the identity of 'hustler' from the street environment and reposition it as connoting a set of valuable creative skills that give them a competitive edge over other participants. An entrepreneurial ethos allows them to view personal sacrifice and exposure to potentially dangerous drugs as smart investments leading to financially stable futures. These discursive moves normalize extractive, and at times dehumanizing, labour relations that offload expenses and risks to workers.

Entities:  

Keywords:  Precarity; clinical trials; creativity; entrepreneurialism; identity; organizations

Year:  2016        PMID: 27524854      PMCID: PMC4978131          DOI: 10.1080/03085147.2015.1113703

Source DB:  PubMed          Journal:  Econ Soc        ISSN: 0308-5147


  10 in total

1.  Challenging assumptions about minority participation in US clinical research.

Authors:  Jill A Fisher; Corey A Kalbaugh
Journal:  Am J Public Health       Date:  2011-10-20       Impact factor: 9.308

2.  "Ready-to-Recruit" or "Ready-to-Consent" Populations?: Informed Consent and the Limits of Subject Autonomy.

Authors:  Jill A Fisher
Journal:  Qual Inq       Date:  2007-09

Review 3.  Paying human subjects in research: where are we, how did we get here, and now what?

Authors:  Ari VanderWalde; Seth Kurzban
Journal:  J Law Med Ethics       Date:  2011       Impact factor: 1.718

4.  Expanding the frame of "voluntariness" in informed consent: structural coercion and the power of social and economic context.

Authors:  Jill A Fisher
Journal:  Kennedy Inst Ethics J       Date:  2013-12

5.  Using "clinical trial diaries" to track patterns of participation for serial healthy volunteers in U.S. phase I studies.

Authors:  Heather B Edelblute; Jill A Fisher
Journal:  J Empir Res Hum Res Ethics       Date:  2015-01-20       Impact factor: 1.742

6.  Stopped hearts, amputated toes and NASA: contemporary legends among healthy volunteers in US phase I clinical trials.

Authors:  Jill A Fisher
Journal:  Sociol Health Illn       Date:  2015-01

7.  Feeding and Bleeding: The Institutional Banalization of Risk to Healthy Volunteers in Phase I Pharmaceutical Clinical Trials.

Authors:  Jill A Fisher
Journal:  Sci Technol Human Values       Date:  2015-03-01

8.  Recruitment practices and the politics of inclusion in cancer clinical trials.

Authors:  Galen Joseph; Daniel Dohan
Journal:  Med Anthropol Q       Date:  2012-09

Review 9.  A risky business: the detection of adverse drug reactions in clinical trials and post-marketing exercises.

Authors:  Oonagh P Corrigan
Journal:  Soc Sci Med       Date:  2002-08       Impact factor: 4.634

10.  Experiencing everyday ethics in context: frontline data collectors perspectives and practices of bioethics.

Authors:  Patricia Kingori
Journal:  Soc Sci Med       Date:  2013-10-25       Impact factor: 4.634

  10 in total
  14 in total

1.  Avoiding Exploitation in Phase I Clinical Trials: More than (Un)Just Compensation.

Authors:  Matt Lamkin; Carl Elliott
Journal:  J Law Med Ethics       Date:  2018-03-27       Impact factor: 1.718

2.  Sacrificial Labour: Social Inequality, Identity Work, and the Damaging Pursuit of Elusive Futures.

Authors:  Torin Monahan; Jill A Fisher
Journal:  Work Employ Soc       Date:  2019-11-08

3.  Captive to the Clinic: Phase I Clinical Trials as Temporal Total Institutions.

Authors:  Quintin Williams; Jill A Fisher
Journal:  Sociol Inq       Date:  2018-04-20

4.  Risk and Emotion Among Healthy Volunteers in Clinical Trials.

Authors:  Marci D Cottingham; Jill A Fisher
Journal:  Soc Psychol Q       Date:  2016-07-29

5.  Healthy Volunteers' Perceptions of the Benefits of Their Participation in Phase I Clinical Trials.

Authors:  Jill A Fisher; Lisa McManus; Megan M Wood; Marci D Cottingham; Julianne M Kalbaugh; Torin Monahan; Rebecca L Walker
Journal:  J Empir Res Hum Res Ethics       Date:  2018-10-08       Impact factor: 1.742

6.  Exceptional Risk: Healthy Volunteers' Perceptions of HIV/AIDS Clinical Trials.

Authors:  Marci D Cottingham; Julianne M Kalbaugh; Teresa Swezey; Jill A Fisher
Journal:  J Acquir Immune Defic Syndr       Date:  2018-10-01       Impact factor: 3.731

7.  Speculating on Precarious Income: Finance Cultures and the Risky Strategies of Healthy Volunteers in Clinical Drug Trials.

Authors:  Jill A Fisher; Megan M Wood; Torin Monahan
Journal:  J Cult Econ       Date:  2020-12-21

8.  Commentary on Zvonareva et al.: Exploring the many meanings of "professional" in research participation.

Authors:  Jill A Fisher
Journal:  Clin Trials       Date:  2019-10-05       Impact factor: 2.486

9.  Women's reasons for participation in a clinical trial for menstrual pain: a qualitative study.

Authors:  Susanne Blödt; Claudia M Witt; Christine Holmberg
Journal:  BMJ Open       Date:  2016-12-13       Impact factor: 2.692

10.  Healthy volunteers' perceptions of risk in US Phase I clinical trials: A mixed-methods study.

Authors:  Jill A Fisher; Lisa McManus; Marci D Cottingham; Julianne M Kalbaugh; Megan M Wood; Torin Monahan; Rebecca L Walker
Journal:  PLoS Med       Date:  2018-11-20       Impact factor: 11.069

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