Hayrullah Yazar1, Abdulhekim Yarbag2, Mehmet Balci3, Bahri Teker4, Pelin Tanyeri5. 1. Department of Medicine, Sakarya University Faculty of Medicine, Sakarya, Istanbul, Turkey. 2. Special Marmara Eye Clinic Center, Sakarya, Istanbul, Turkey. 3. Infectious Diseases and Clinical Microbiology, Bolu State Hospital, Bolu, Istanbul, Turkey. 4. Infectious Diseases and Clinical Microbiology, Nisa Hospital, Istanbul, Turkey. 5. Department of Pharmacology, Sakarya University Faculty of Medicine, Sakarya, Istanbul, Turkey.
Abstract
OBJECTIVE: To compare the efficacy of classical treatment and povidone-iodine treatment for adenoviral conjunctivitis. METHODS: This retrospective study was conducted at the Centre of Marmara Eye Health, Sakarya, Turkey, between January 2011 and February 2014, and comprised adult patients suffering from adenoviral conjunctivitis. The participants were randomly divided into two groups. Group I was given povidone-iodine solution while Group II was given the classical treatment and was taken as control. Povidone-iodine treatment was administered as three drops three times per day. The classical treatment comprised three drops of trifluorothymidine three times per day. Treatment were continued for two weeks. The patients who had not recovered in this time frame were defined as 'late recovering' patients. SPSS 23 was used for data analysis. RESULTS: Of the 112 participants, there were 56(50%) in each group. In Group I, 54(96.4%) patients recovered in two weeks, while 2(3.6%) took more time. In Group II, 33(58.9%) patients recovered in two weeks while 23(41.1%) took more time (p<0.001). Overall, 92(82.1%) patients had familial transmission-contamination. CONCLUSIONS: A new treatment protocol of povidone-iodine was used safely in patients with adenoviral conjunctivitis. Familial transmission was found very important to adenoviral conjunctivitis infection.
RCT Entities:
OBJECTIVE: To compare the efficacy of classical treatment and povidone-iodine treatment for adenoviral conjunctivitis. METHODS: This retrospective study was conducted at the Centre of Marmara Eye Health, Sakarya, Turkey, between January 2011 and February 2014, and comprised adult patients suffering from adenoviral conjunctivitis. The participants were randomly divided into two groups. Group I was given povidone-iodine solution while Group II was given the classical treatment and was taken as control. Povidone-iodine treatment was administered as three drops three times per day. The classical treatment comprised three drops of trifluorothymidine three times per day. Treatment were continued for two weeks. The patients who had not recovered in this time frame were defined as 'late recovering' patients. SPSS 23 was used for data analysis. RESULTS: Of the 112 participants, there were 56(50%) in each group. In Group I, 54(96.4%) patients recovered in two weeks, while 2(3.6%) took more time. In Group II, 33(58.9%) patients recovered in two weeks while 23(41.1%) took more time (p<0.001). Overall, 92(82.1%) patients had familial transmission-contamination. CONCLUSIONS: A new treatment protocol of povidone-iodine was used safely in patients with adenoviral conjunctivitis. Familial transmission was found very important to adenoviral conjunctivitis infection.
Authors: Ellen Shorter; Meredith Whiteside; Jennifer Harthan; Mathew S Margolis; Andrew T Hartwick; Spencer Johnson; Mary Migneco; Christina Morettin; Christian K Olson; Julia Huecker; Tammy Than; Mae O Gordon Journal: Ocul Surf Date: 2019-08-08 Impact factor: 5.033
Authors: Meredith M Whiteside; Ellen S Shorter; Mathew S Margolis; Fatima Alvi; Julia B Huecker; Tammy P Than; Mary K Migneco; Jennifer S Harthan; Christina E Morettin; Andrew T E Hartwick; Spencer D Johnson; Chamila D Perera; Mae O Gordon Journal: Optom Vis Sci Date: 2021-05-01 Impact factor: 1.973