Literature DB >> 27524294

Chemical Modulation of Cell Fate in Stem Cell Therapeutics and Regenerative Medicine.

Kai Liu1, Chen Yu1, Min Xie1, Ke Li1, Sheng Ding2.   

Abstract

Regenerative medicine aims to repair and regenerate injured tissues and restore their impaired functions. Recent developments in stem cell biology have attracted significant interest in their applications in regenerative medicine. Chemical approaches using small molecules have yielded exciting results in induction and differentiation of pluripotent stem cells, lineage conversion of somatic cells, and ex vivo as well as in vivo modulation of adult stem cells. In this review, we discuss recent progress, new insights, and future challenges of the chemical approaches in stem cell biology and regenerative medicine.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Mesh：

Substances：

Year:  2016        PMID： 27524294     DOI： 10.1016/j.chembiol.2016.07.007

Source DB:  PubMed          Journal:  Cell Chem Biol        ISSN： 2451-9448            Impact factor:   8.116


  15 in total

1.  Steroid Hormones and the Physiological Regulation of Tissue-Resident Stem Cells: Lessons from the Drosophila Ovary.

Authors:  Elizabeth T Ables; Daniela Drummond-Barbosa
Journal:  Curr Stem Cell Rep       Date:  2017-02-01

2.  MYOCD is Required for Cardiomyocyte-like Cells Induction from Human Urine Cells and Fibroblasts Through Remodeling Chromatin.

Authors:  Xiangyu Zhang; Lijun Chen; Xingnan Huang; Huan Chen; Baomei Cai; Yue Qin; Yating Chen; Sihua Ou; Xiaoxi Li; Zichao Wu; Ziyu Feng; Mengying Zeng; Wenjing Guo; Heying Li; Chunhua Zhou; Shengyong Yu; Mengjie Pan; Jing Liu; Kai Kang; Shangtao Cao; Duanqing Pei
Journal:  Stem Cell Rev Rep       Date:  2022-03-04       Impact factor: 6.692

3.  Transient Activation of Reprogramming Transcription Factors Using Protein Transduction Facilitates Conversion of Human Fibroblasts Toward Cardiomyocyte-Like Cells.

Authors:  Zaniar Ghazizadeh; Hassan Rassouli; Hananeh Fonoudi; Mehdi Alikhani; Mahmood Talkhabi; Amir Darbandi-Azar; Shuibing Chen; Hossein Baharvand; Nasser Aghdami; Ghasem Hosseini Salekdeh
Journal:  Mol Biotechnol       Date:  2017-06       Impact factor: 2.695

4.  BET bromodomain inhibitors regulate keratinocyte plasticity.

Authors:  Gabi Schutzius; Christian Kolter; Sebastian Bergling; Federico Tortelli; Florian Fuchs; Steffen Renner; Vito Guagnano; Simona Cotesta; Heinrich Rueeger; Michael Faller; Laure Bouchez; Adrian Salathe; Florian Nigsch; Shola M Richards; Malvina Louis; Viktoria Gruber; Alexandra Aebi; Jonathan Turner; Frederic Grandjean; Jun Li; Chris Dimitri; Jason R Thomas; Markus Schirle; Jutta Blank; Peter Drueckes; Andrea Vaupel; Ralph Tiedt; Paul W Manley; Julia Klopp; Rene Hemmig; Florence Zink; Nelly Leroy; Walter Carbone; Guglielmo Roma; Caroline Gubser Keller; Natalie Dales; Armin Beyerbach; Alfred Zimmerlin; Debora Bonenfant; Remi Terranova; Amy Berwick; Sukhdeep Sahambi; Aimee Reynolds; Lori L Jennings; Heinz Ruffner; Peter Tarsa; Tewis Bouwmeester; Vickie Driver; Mathias Frederiksen; Felix Lohmann; Susan Kirkland
Journal:  Nat Chem Biol       Date:  2021-01-18       Impact factor: 15.040

5.  Inhibition of Syk promotes chemical reprogramming of fibroblasts via metabolic rewiring and H2 S production.

Authors:  Weiyun Wang; Shaofang Ren; Yunkun Lu; Xi Chen; Juanjuan Qu; Xiaojie Ma; Qian Deng; Zhensheng Hu; Yan Jin; Ziyu Zhou; Wenyan Ge; Yibing Zhu; Nannan Yang; Qin Li; Jiaqi Pu; Guo Chen; Cunqi Ye; Hao Wang; Xiaoyang Zhao; Zhiqiang Liu; Saiyong Zhu
Journal:  EMBO J       Date:  2021-04-28       Impact factor: 14.012

6.  Pharmacological activation of TAZ enhances osteogenic differentiation and bone formation of adipose-derived stem cells.

Authors:  Yumin Zhu; Yaping Wu; Jie Cheng; Qiong Wang; Zhongwu Li; Yanling Wang; Dongmiao Wang; Hua Wang; Weibing Zhang; Jinhai Ye; Hongbing Jiang; Lin Wang
Journal:  Stem Cell Res Ther       Date:  2018-03-07       Impact factor: 6.832

7.  Highly efficient and expedited hepatic differentiation from human pluripotent stem cells by pure small-molecule cocktails.

Authors:  Cong Du; Yuan Feng; Dongbo Qiu; Yan Xu; Mao Pang; Nan Cai; Andy Peng Xiang; Qi Zhang
Journal:  Stem Cell Res Ther       Date:  2018-03-09       Impact factor: 6.832

8.  Human Induced Pluripotent Stem Cells : Clinical Significance and Applications in Neurologic Diseases.

Authors:  Eun-Ah Chang; Sung-Won Jin; Myung-Hyun Nam; Sang-Dae Kim
Journal:  J Korean Neurosurg Soc       Date:  2019-08-09

Review 9.  The role of small molecules in cell and gene therapy.

Authors:  Lewis L Brayshaw; Carlos Martinez-Fleites; Takis Athanasopoulos; Thomas Southgate; Laurent Jespers; Christopher Herring
Journal:  RSC Med Chem       Date:  2020-12-24

Review 10.  Controlling stem cell fate using cold atmospheric plasma.

Authors:  Fei Tan; Yin Fang; Liwei Zhu; Mohamed Al-Rubeai
Journal:  Stem Cell Res Ther       Date:  2020-08-26       Impact factor: 6.832
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.