Mei Yang1, Li Zhong1, Ying-Hsiang Lee1, Vaibhav R Vaidya1, Samuel J Asirvatham1, Michael J Ackerman1, Sorin V Pislaru1, Rakesh M Suri1, Joshua P Slusser2, David O Hodge3, Yu-Tang Wang4, Yong-Mei Cha5. 1. Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA. 2. Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA. 3. Department of Health Sciences, Research, Mayo Clinic, Jacksonville, FL 32224, USA. 4. Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China. Electronic address: wyt301@sina.com. 5. Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA. Electronic address: ycha@mayo.edu.
Abstract
BACKGROUND: In patients with frequent premature ventricular contractions (PVCs), little is known about the profile of PVCs and the outcome of treatment in patients with mitral valve prolapse (MVP) compared to those without MVP. METHODS AND RESULTS: Patients with documented PVCs between January 2001 and October 2012 were divided into 2 groups: MVP and non-MVP. The PVC characteristics, efficacy of therapy, and outcome were compared between the 2 groups. A total of 112 patients with MVP and 952 without MVP were identified. The frequency of PVCs was similar between the 2 groups (P>.05). In patients who underwent cardiac mapping, PVCs originating in papillary muscles (26.7% vs 2.3%; P<.001) and fascicle (13.3% vs 3.4%; P<.001) were more frequently seen in the MVP group than in the non-MVP group, which raises the difficulty of catheter ablation. The 2 groups had similar response to catheter ablation or medical therapy (P>.05). The survival rate was similar between the 2 groups (P=.95). CONCLUSION: In patients with significant PVC burden, MVP patients had similar PVC frequency, treatment outcome, and survival rate to those without MVP.
BACKGROUND: In patients with frequent premature ventricular contractions (PVCs), little is known about the profile of PVCs and the outcome of treatment in patients with mitral valve prolapse (MVP) compared to those without MVP. METHODS AND RESULTS:Patients with documented PVCs between January 2001 and October 2012 were divided into 2 groups: MVP and non-MVP. The PVC characteristics, efficacy of therapy, and outcome were compared between the 2 groups. A total of 112 patients with MVP and 952 without MVP were identified. The frequency of PVCs was similar between the 2 groups (P>.05). In patients who underwent cardiac mapping, PVCs originating in papillary muscles (26.7% vs 2.3%; P<.001) and fascicle (13.3% vs 3.4%; P<.001) were more frequently seen in the MVP group than in the non-MVP group, which raises the difficulty of catheter ablation. The 2 groups had similar response to catheter ablation or medical therapy (P>.05). The survival rate was similar between the 2 groups (P=.95). CONCLUSION: In patients with significant PVC burden, MVP patients had similar PVC frequency, treatment outcome, and survival rate to those without MVP.
Authors: Edmond M Cronin; Frank M Bogun; Philippe Maury; Petr Peichl; Minglong Chen; Narayanan Namboodiri; Luis Aguinaga; Luiz Roberto Leite; Sana M Al-Khatib; Elad Anter; Antonio Berruezo; David J Callans; Mina K Chung; Phillip Cuculich; Andre d'Avila; Barbara J Deal; Paolo Della Bella; Thomas Deneke; Timm-Michael Dickfeld; Claudio Hadid; Haris M Haqqani; G Neal Kay; Rakesh Latchamsetty; Francis Marchlinski; John M Miller; Akihiko Nogami; Akash R Patel; Rajeev Kumar Pathak; Luis C Saenz Morales; Pasquale Santangeli; John L Sapp; Andrea Sarkozy; Kyoko Soejima; William G Stevenson; Usha B Tedrow; Wendy S Tzou; Niraj Varma; Katja Zeppenfeld Journal: J Interv Card Electrophysiol Date: 2020-10 Impact factor: 1.900
Authors: Edmond M Cronin; Frank M Bogun; Philippe Maury; Petr Peichl; Minglong Chen; Narayanan Namboodiri; Luis Aguinaga; Luiz Roberto Leite; Sana M Al-Khatib; Elad Anter; Antonio Berruezo; David J Callans; Mina K Chung; Phillip Cuculich; Andre d'Avila; Barbara J Deal; Paolo Della Bella; Thomas Deneke; Timm-Michael Dickfeld; Claudio Hadid; Haris M Haqqani; G Neal Kay; Rakesh Latchamsetty; Francis Marchlinski; John M Miller; Akihiko Nogami; Akash R Patel; Rajeev Kumar Pathak; Luis C Sáenz Morales; Pasquale Santangeli; John L Sapp; Andrea Sarkozy; Kyoko Soejima; William G Stevenson; Usha B Tedrow; Wendy S Tzou; Niraj Varma; Katja Zeppenfeld Journal: Europace Date: 2019-08-01 Impact factor: 5.214