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Literature DB >> 27521599

Inflammation and cancer: tissue regeneration gone awry.

Abstract

Unresolved chronic inflammation is implicated in all stages of cancer development and an inflammatory tumor microenvironment is considered a hallmark of cancer. Signaling pathways involved in normal tissue regeneration and repair are dysregulated both in chronic inflammation and cancer. Here, we review some of the recently identified signaling cascades and unexpected functions of stromal cells that affect both tissue regeneration and tumorigenesis in colon and pancreatic cancer, which may pave the way for the development of novel therapeutic strategies.

Entities: Disease

Mesh：

Year: 2016 PMID： 27521599 DOI： 10.1016/j.ceb.2016.07.010

Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382

Keyword Cloud
Cited

41 in total

1. Genetic variants in the platelet-derived growth factor subunit B gene associated with pancreatic cancer risk.

Authors: Bensong Duan; Jiangfeng Hu; Hongliang Liu; Yanru Wang; Hongyu Li; Shun Liu; Jichun Xie; Kouros Owzar; James Abbruzzese; Herbert Hurwitz; Hengjun Gao; Qingyi Wei
Journal: Int J Cancer Date: 2017-12-04 Impact factor: 7.396

2. Substrate curvature regulates cell migration.

Authors: Xiuxiu He; Yi Jiang
Journal: Phys Biol Date: 2017-05-23 Impact factor: 2.583

Review 3. Schwann cells: a new player in the tumor microenvironment.

Authors: Yuri L Bunimovich; Anton A Keskinov; Galina V Shurin; Michael R Shurin
Journal: Cancer Immunol Immunother Date: 2016-11-24 Impact factor: 6.968

4. Obesity-Associated Extracellular Matrix Remodeling Promotes a Macrophage Phenotype Similar to Tumor-Associated Macrophages.

Authors: Nora L Springer; Neil M Iyengar; Rohan Bareja; Akanksha Verma; Maxine S Jochelson; Dilip D Giri; Xi K Zhou; Olivier Elemento; Andrew J Dannenberg; Claudia Fischbach
Journal: Am J Pathol Date: 2019-07-16 Impact factor: 4.307

Review 5. Proteoglycan neofunctions: regulation of inflammation and autophagy in cancer biology.

Authors: Liliana Schaefer; Claudia Tredup; Maria A Gubbiotti; Renato V Iozzo
Journal: FEBS J Date: 2016-12-07 Impact factor: 5.542

6. Mediators of Inflammation-Driven Expansion, Trafficking, and Function of Tumor-Infiltrating MDSCs.

Authors: Charles S Tannenbaum; Patricia A Rayman; Paul G Pavicic; Jin Sub Kim; Wei Wei; Alexandra Polefko; Wesley Wallace; Brian I Rini; Gareth Morris-Stiff; Daniela S Allende; Thomas Hamilton; James H Finke; C Marcela Diaz-Montero
Journal: Cancer Immunol Res Date: 2019-08-22 Impact factor: 11.151

7. A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer, the Pirc rat (F344/NTac-Apc^am1137).

Authors: Michele Navarra; Angelo Pietro Femia; Andrea Romagnoli; Katia Tortora; Cristina Luceri; Santa Cirmi; Nadia Ferlazzo; Giovanna Caderni
Journal: Eur J Nutr Date: 2019-03-27 Impact factor: 5.614

Inflammation and cancer: tissue regeneration gone awry.

1. Genetic variants in the platelet-derived growth factor subunit B gene associated with pancreatic cancer risk.

2. Substrate curvature regulates cell migration.

Review 3. Schwann cells: a new player in the tumor microenvironment.

4. Obesity-Associated Extracellular Matrix Remodeling Promotes a Macrophage Phenotype Similar to Tumor-Associated Macrophages.

Review 5. Proteoglycan neofunctions: regulation of inflammation and autophagy in cancer biology.

6. Mediators of Inflammation-Driven Expansion, Trafficking, and Function of Tumor-Infiltrating MDSCs.

7. A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer, the Pirc rat (F344/NTac-Apc^am1137).

Review 8. NF-κB, inflammation, immunity and cancer: coming of age.

Review 9. Implications of macrophage polarization in autoimmunity.

Review 10. Targeting tumor-associated macrophages by anti-tumor Chinese materia medica.

Inflammation and cancer: tissue regeneration gone awry.

1. Genetic variants in the platelet-derived growth factor subunit B gene associated with pancreatic cancer risk.

2. Substrate curvature regulates cell migration.

Review 3. Schwann cells: a new player in the tumor microenvironment.

4. Obesity-Associated Extracellular Matrix Remodeling Promotes a Macrophage Phenotype Similar to Tumor-Associated Macrophages.

Review 5. Proteoglycan neofunctions: regulation of inflammation and autophagy in cancer biology.

6. Mediators of Inflammation-Driven Expansion, Trafficking, and Function of Tumor-Infiltrating MDSCs.

7. A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer, the Pirc rat (F344/NTac-Apcam1137).

Review 8. NF-κB, inflammation, immunity and cancer: coming of age.

Review 9. Implications of macrophage polarization in autoimmunity.

Review 10. Targeting tumor-associated macrophages by anti-tumor Chinese materia medica.

7. A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer, the Pirc rat (F344/NTac-Apc^am1137).