Literature DB >> 27520876

The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans.

Panu K Luukkonen1, You Zhou2, Tuulia Hyötyläinen3, Marja Leivonen4, Johanna Arola5, Marju Orho-Melander6, Matej Orešič3, Hannele Yki-Järvinen7.   

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Year:  2016        PMID： 27520876     DOI： 10.1016/j.jhep.2016.07.045

Source DB:  PubMed          Journal:  J Hepatol        ISSN： 0168-8278            Impact factor:   25.083


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  45 in total

1.  Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease.

Authors:  Panu K Luukkonen; Taru Tukiainen; Anne Juuti; Henna Sammalkorpi; P A Nidhina Haridas; Onni Niemelä; Johanna Arola; Marju Orho-Melander; Antti Hakkarainen; Petri T Kovanen; Om Dwivedi; Leif Groop; Leanne Hodson; Amalia Gastaldelli; Tuulia Hyötyläinen; Matej Orešič; Hannele Yki-Järvinen
Journal:  JCI Insight       Date:  2020-03-12

2.  Independent and additive effects of PNPLA3 and TM6SF2 polymorphisms on the development of non-B, non-C hepatocellular carcinoma.

Authors:  Maneerat Raksayot; Natthaya Chuaypen; Apichaya Khlaiphuengsin; Nutcha Pinjaroen; Sombat Treeprasertsuk; Yong Poovorawan; Yasuhito Tanaka; Pisit Tangkijvanich
Journal:  J Gastroenterol       Date:  2018-11-30       Impact factor: 7.527

Review 3.  Hepatic Steatosis in the Pediatric Population: An Overview of Pathophysiology, Genetics, and Diagnostic Workup.

Authors:  Claudia Phen; Charina M Ramirez
Journal:  Clin Liver Dis (Hoboken)       Date:  2021-04-13

4.  The PNPLA3 I148M variant is associated with transaminase elevations in type 2 diabetes patients treated with basal insulin peglispro.

Authors:  S Pillai; S Duvvuru; P Bhatnagar; W Foster; M Farmen; S Shankar; C Harris; E Bastyr; B Hoogwerf; A Haupt
Journal:  Pharmacogenomics J       Date:  2017-11-21       Impact factor: 3.550

5.  The rs626283 Variant in the MBOAT7 Gene is Associated with Insulin Resistance and Fatty Liver in Caucasian Obese Youth.

Authors:  Giuseppina R Umano; Sonia Caprio; Anna Di Sessa; Naga Chalasani; Daniel J Dykas; Bridget Pierpont; Allen E Bale; Nicola Santoro
Journal:  Am J Gastroenterol       Date:  2018-02-27       Impact factor: 10.864

6.  Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease.

Authors:  Robert N Helsley; Venkateshwari Varadharajan; Amanda L Brown; Anthony D Gromovsky; Rebecca C Schugar; Iyappan Ramachandiran; Kevin Fung; Mohammad Nasser Kabbany; Rakhee Banerjee; Chase K Neumann; Chelsea Finney; Preeti Pathak; Danny Orabi; Lucas J Osborn; William Massey; Renliang Zhang; Anagha Kadam; Brian E Sansbury; Calvin Pan; Jessica Sacks; Richard G Lee; Rosanne M Crooke; Mark J Graham; Madeleine E Lemieux; Valentin Gogonea; John P Kirwan; Daniela S Allende; Mete Civelek; Paul L Fox; Lawrence L Rudel; Aldons J Lusis; Matthew Spite; J Mark Brown
Journal:  Elife       Date:  2019-10-17       Impact factor: 8.140

Review 7.  Nutrigenomics and Nutrigenetics in Metabolic- (Dysfunction) Associated Fatty Liver Disease: Novel Insights and Future Perspectives.

Authors:  Marcello Dallio; Mario Romeo; Antonietta Gerarda Gravina; Mario Masarone; Tiziana Larussa; Ludovico Abenavoli; Marcello Persico; Carmelina Loguercio; Alessandro Federico
Journal:  Nutrients       Date:  2021-05-15       Impact factor: 5.717

8.  MBOAT7 rs641738 variant and hepatocellular carcinoma in non-cirrhotic individuals.

Authors:  Benedetta Donati; Paola Dongiovanni; Stefano Romeo; Marica Meroni; Misti McCain; Luca Miele; Salvatore Petta; Silvia Maier; Chiara Rosso; Laura De Luca; Ester Vanni; Stefania Grimaudo; Renato Romagnoli; Fabio Colli; Flaminia Ferri; Rosellina Margherita Mancina; Paula Iruzubieta; Antonio Craxi; Anna Ludovica Fracanzani; Antonio Grieco; Stefano Ginanni Corradini; Alessio Aghemo; Massimo Colombo; Giorgio Soardo; Elisabetta Bugianesi; Helen Reeves; Quentin M Anstee; Silvia Fargion; Luca Valenti
Journal:  Sci Rep       Date:  2017-07-03       Impact factor: 4.379

9.  Evaluation of Polygenic Determinants of Non-Alcoholic Fatty Liver Disease (NAFLD) By a Candidate Genes Resequencing Strategy.

Authors:  Alessia Di Costanzo; Francesca Belardinilli; Diego Bailetti; Marialuisa Sponziello; Laura D'Erasmo; Licia Polimeni; Francesco Baratta; Daniele Pastori; Fabrizio Ceci; Anna Montali; Gabriella Girelli; Bruna De Masi; Antonio Angeloni; Giuseppe Giannini; Maria Del Ben; Francesco Angelico; Marcello Arca
Journal:  Sci Rep       Date:  2018-02-27       Impact factor: 4.379

Review 10.  Gene-Environmental Interactions as Metabolic Drivers of Nonalcoholic Steatohepatitis.

Authors:  Somaya Albhaisi; Arun J Sanyal
Journal:  Front Endocrinol (Lausanne)       Date:  2021-05-10       Impact factor: 5.555
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