| Literature DB >> 27520277 |
Anahita Kiasatdolatabadi1, Nasrin Lotfibakhshaiesh1, Meysam Yazdankhah1,2, Somayeh Ebrahimi-Barough1, Mina Jafarabadi3, Arman Ai4, Esmaeil Sadroddiny5, Jafar Ai6.
Abstract
Cerebral palsy (CP) is a neuromuscular disease due to injury in the infant's brain. The CP disorder causes many neurologic dysfunctions in the patient. Various treatment methods have been used for the management of CP disorder. However, there has been no absolute cure for this condition. Furthermore, some of the procedures which are currently used for relief of symptoms in CP cause discomfort or side effects in the patient. Recently, stem cell therapy has attracted a huge interest as a new therapeutic method for treatment of CP. Several investigations in animal and human with CP have demonstrated positive potential of stem cell transplantation for the treatment of CP disorder. The ultimate goal of this therapeutic method is to harness the regenerative capacity of the stem cells causing a formation of new tissues to replace the damaged tissue. During the recent years, there have been many investigations on stem cell therapy. However, there are still many unclear issues regarding this method and high effort is needed to create a technology as a perfect treatment. This review will discuss the scientific background of stem cell therapy for cerebral palsy including evidences from current clinical trials.Entities:
Keywords: Cerebral palsy; Clinical trials; Stem cell; Treatment
Mesh：
Year: 2016 PMID： 27520277 DOI： 10.1007/s12035-016-0030-0
Source DB: PubMed Journal: Mol Neurobiol ISSN： 0893-7648 Impact factor: 5.590