Literature DB >> 27518967

Effects of reserpine, chlorpromazine, imipramine and amitriptyline on urinary excretion of adenosine 3' 5' cyclic monophosphate in rats.

A M Keatinge1,2, K Sinanan1,2, W C Love1,2.   

Abstract

RATS were treated with reserpine, chlorpromazine, imipramine and amitriptyline to assess the effect of these drugs on the urinary excretion of adenosine 3' 5'-cyclic monophosphate (cAMP).Reserpine led to a decrease in the urinary excretion of cAMP. The tricyclic antidepressants, imipramine and amitriptyline, led to an increase in the urinary excretion of cAMP. Chlorpromazine had no appreciable effect on urinary excretion of cAMP.

Entities:  

Year:  1975        PMID： 27518967     DOI： 10.1007/BF02939023

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN： 0021-1265            Impact factor:   1.568


  10 in total

1.  The metabolism and excretion of S35-chlorpromazine by the rat.

Authors:  J L EMMERSON; T S MIYA
Journal:  J Pharmacol Exp Ther       Date:  1962-08       Impact factor: 4.030

2.  Urinary cyclic AMP IN 'ENDOGENOUS' AND 'NEUROTIC' DEPRESSION.

Authors:  K Sinanan; A M Keatinge; P G Beckett; W C Love
Journal:  Br J Psychiatry       Date:  1975-01       Impact factor: 9.319

3.  A simple and sensitive saturation assay method for the measurement of adenosine 3':5'-cyclic monophosphate.

Authors:  B L Brown; J D Albano; R P Ekins; A M Sgherzi
Journal:  Biochem J       Date:  1971-02       Impact factor: 3.857

4.  Stimulated formation of adenosine 3',5'-monophosphate by desipramine in brain slices.

Authors:  T Kodama; Y Matsukado; T Suzuki; S Tanaka; H Shimizu
Journal:  Biochim Biophys Acta       Date:  1971-10

5.  Letter: Urinary cyclic AMP and depression.

Authors:  K Sinanan; W Clayton-Love; A M Keatinge
Journal:  Br J Psychiatry       Date:  1974-12       Impact factor: 9.319

6.  Urinary cyclic AMP excretion in depression and mania. Effects of levodopa and lithium carbonate.

Authors:  M I Paul; H Cramer; F K Goodwin
Journal:  Arch Gen Psychiatry       Date:  1971-04

7.  Cyclic adenosine monophosphate phosphodiesterase in brain: effect on anxiety.

Authors:  B Beer; M Chasin; D E Clody; J R Vogel
Journal:  Science       Date:  1972-04-28       Impact factor: 47.728

8.  Accumulation of cyclic adenosine monophosphate in incubated slices of brain tissue. 1. Structure-activity relationships of agonists and antagonists of biogenic amines and of tricyclic tranquilizers and antidepressants.

Authors:  M Huang; J W Daly
Journal:  J Med Chem       Date:  1972-05       Impact factor: 7.446

9.  Cyclic A.M.P. in depression and mania.

Authors:  E N Ramsden
Journal:  Lancet       Date:  1970-07-11       Impact factor: 79.321

10.  3',5' cyclic adenosine monophosphate in depression and mania.

Authors:  Y H Abdulla; K Hamadah
Journal:  Lancet       Date:  1970-02-21       Impact factor: 79.321
  10 in total

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