Literature DB >> 27518566

Identification of Causal Genetic Drivers of Human Disease through Systems-Level Analysis of Regulatory Networks.

James C Chen, Mariano J Alvarez, Flaminia Talos, Harshil Dhruv, Gabrielle E Rieckhof, Archana Iyer, Kristin L Diefes, Kenneth Aldape, Michael Berens, Michael M Shen, Andrea Califano.   

Abstract

Entities:  

Year:  2016        PMID： 27518566     DOI： 10.1016/j.cell.2016.07.036

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


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  3 in total

1.  Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas.

Authors:  Jennifer K Lue; Sathyen A Prabhu; Yuxuan Liu; Yulissa Gonzalez; Akanksha Verma; Prabhjot S Mundi; Nebiyu Abshiru; Jeannie M Camarillo; Swasti Mehta; Emily I Chen; Changhong Qiao; Renu Nandakumar; Serge Cremers; Neil L Kelleher; Olivier Elemento; Jennifer E Amengual
Journal:  Clin Cancer Res       Date:  2019-04-12       Impact factor: 13.801

2.  Predicting and affecting response to cancer therapy based on pathway-level biomarkers.

Authors:  Rotem Ben-Hamo; Adi Jacob Berger; Nancy Gavert; Mendy Miller; Guy Pines; Roni Oren; Eli Pikarsky; Cyril H Benes; Tzahi Neuman; Yaara Zwang; Sol Efroni; Gad Getz; Ravid Straussman
Journal:  Nat Commun       Date:  2020-07-03       Impact factor: 14.919

3.  KLF4, a Key Regulator of a Transitive Triplet, Acts on the TGF-β Signaling Pathway and Contributes to High-Altitude Adaptation of Tibetan Pigs.

Authors:  Tao Wang; Yuanyuan Guo; Shengwei Liu; Chaoxin Zhang; Tongyan Cui; Kun Ding; Peng Wang; Xibiao Wang; Zhipeng Wang
Journal:  Front Genet       Date:  2021-04-15       Impact factor: 4.599
  3 in total

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