| Literature DB >> 27518556 |
Abstract
Chawla and colleagues find that interleukin-33 is a critical controller of brown and beige adipocyte thermogenesis. Its primary impact is on the splicing of transcripts encoding uncoupling protein-1, resulting in uncoupled respiration and effective heat generation. Interleukin-33 acts perinatally to ensure adaptive thermogenesis lifelong.Entities:
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Year: 2016 PMID： 27518556 DOI： 10.1016/j.cell.2016.07.051
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582