Literature DB >> 27517404

The immunogenic properties of a highly purified insulin preparation.

N T Manning1, M I Drury1.   

Abstract

Twenty patients who had never previously received insulin were treated with a highly purified preparation (NPH LEO in R.I. quality). Insulin antibody estimations were performed over a 14 to 19 month period. Detectable amounts of antibodies were formed by 18 of the 20 patients. The levels were lower than those found in patients on conventional insulins but moderate levels were found in 7 patients. No correlation was found between the development of antibodies and changes in insulin requirement.

Entities:  

Year:  1979        PMID： 27517404     DOI： 10.1007/BF02938066

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN： 0021-1265            Impact factor:   1.568


  19 in total

1.  Insulin antibodies in aetiology of labile diabetes.

Authors:  K Dixon; P D Exon; H R Hughes
Journal:  Lancet       Date:  1972-02-12       Impact factor: 79.321

2.  [Serum I-125 insulin IgG binding capacity in diabetic patients on a long-term insulin treatment, with reference to indications for monocomponent insulin therapy].

Authors:  B Bruni; R Castellazzi; M Osenda; G Papotti; G L Turco
Journal:  Minerva Med       Date:  1974-03-17       Impact factor: 4.806

3.  Immunogenicity of "single peak" beef-pork insulin in diabetic subjects.

Authors:  J J Tantillo; J H Karam; K C Burrill; M A Jones; G M Grodsky; P H Forsham
Journal:  Diabetes       Date:  1974-04       Impact factor: 9.461

4.  The glomerular basement membrane of the rabbit kidney on long-term treatment with heterologous insulin preparations of different purity.

Authors:  H Wehner; H Huber; K H Kronenberg
Journal:  Diabetologia       Date:  1973-08       Impact factor: 10.122

5.  Immunogenicity of insulin.

Authors:  M A Root; R E Chance; J A Galloway
Journal:  Diabetes       Date:  1972       Impact factor: 9.461

6.  Clinical aspects of insulin--antigenicity.

Authors:  J Schlichtkrull; J Brange; A H Christiansen; O Hallund; L G Heding; K H Jorgensen
Journal:  Diabetes       Date:  1972       Impact factor: 9.461

7.  Insulin antibodies in the serum of diabetic children treated from the diagnosis of the disease with highly purified insulins.

Authors:  H K Akerblom; A L Mäkelä
Journal:  Acta Paediatr Scand Suppl       Date:  1977

8.  Serum insulin, insulin antibodies and insulin requirement in the first period of insulin treatment in non-insulin resistant diabetics.

Authors:  A Lev-Ran; L Ratt; N Gersht
Journal:  Acta Diabetol Lat       Date:  1975 Jan-Feb

9.  Circulating antibodies in diabetics treated with conventional and purified insulins.

Authors:  L J Klaff; A I Vinik; M Berelowitz; W P Jackson
Journal:  S Afr Med J       Date:  1978-07-22

10.  Insulin-I131 metabolism in human subjects: demonstration of insulin binding globulin in the circulation of insulin treated subjects.

Authors:  S A BERSON; R S YALOW; A BAUMAN; M A ROTHSCHILD; K NEWERLY
Journal:  J Clin Invest       Date:  1956-02       Impact factor: 14.808
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