Literature DB >> 2751457

Identification and significance of multinucleate tumor cells in retinoblastoma.

M A Howard1, T P Dryja, D S Walton, D M Albert.   

Abstract

Multinucleate tumor cells were observed in a case of a retinal tumor suspected to be a retinoma (retinocytoma). On electron microscopy, these cells had characteristics of retinoblastoma. Similar cells were observed in an irradiated model of retinoblastoma grown in a nude mouse. We suggest that the presence of these cells indicates differentiation and/or regression of the tumor.

Entities:  

Mesh：

Year:  1989        PMID： 2751457     DOI： 10.1001/archopht.1989.01070020087037

Source DB:  PubMed          Journal:  Arch Ophthalmol        ISSN： 0003-9950


  4 in total

1.  Integrin-linked kinase regulates senescence in an Rb-dependent manner in cancer cell lines.

Authors:  Rose Duminuco; Jake W Noble; Joseph Goody; Manju Sharma; Bruce R Ksander; Calvin D Roskelley; Michael E Cox; Julia Mills
Journal:  Cell Cycle       Date:  2015       Impact factor: 4.534

2.  T-type calcium channels as therapeutic targets for treating "giant" retinoblastoma cancer cells.

Authors:  Emilio Carbone
Journal:  Pflugers Arch       Date:  2021-09-07       Impact factor: 3.657

3.  Giant Y79 retinoblastoma cells contain functionally active T-type calcium channels.

Authors:  Sooyun Kim; Segundo Jose Guzman; Dong Hyun Jo; Chang Sik Cho; Jeong Hun Kim
Journal:  Pflugers Arch       Date:  2021-08-15       Impact factor: 4.458

4.  Regulation of mitotic cytoskeleton dynamics and cytokinesis by integrin-linked kinase in retinoblastoma cells.

Authors:  William K A Sikkema; Arend Strikwerda; Manju Sharma; Kiran Assi; Baljinder Salh; Michael E Cox; Julia Mills
Journal:  PLoS One       Date:  2014-06-09       Impact factor: 3.240
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.