Literature DB >> 27513396

The effects of conscious sedation with nitrous oxide/oxygen on cognitive functions.

Sara Samur Ergüven1, Ertan Ali Delilbaşi2, Berrin İşik3, Ferhunde Öktem4.   

Abstract

BACKGROUND/AIM: The aim of this study was to investigate the effects of conscious sedation with 40% nitrous oxide/oxygen (N2O/O2) on cognitive functions.
MATERIALS AND METHODS: Forty dental patients referred to the sedation unit at Gazi University Faculty of Dentistry Department of Oral and Maxillofacial Surgery received a combination of 40% N2O/O2 inhalation for conscious sedation. Psychometric tests were applied three times: before sedation, during sedation, and at the end of the recovery, for assessing cognitive functions.
RESULTS: The results of this study showed that the 40% N2O/O2 combination impaired cognitive functions during the conscious sedation. Recovery of most of the cognitive functions occurred 15 min after sedation. However, in addition to the persistence of 'hypnotic effects' and 'sensations of isolation' during the recovery period, 'motor loss value' showed more cognitive impairment 15 min after sedation than before the sedation period, and, thus, the ability to execute fine motor skills was not totally recovered by then.
CONCLUSION: The results of this study could be crucial for informing patients about avoiding attentive activities soon after conscious sedation via 40% N2O/O2.

Entities:  

Keywords:  Cognitive symptoms; conscious sedation; nitrous oxide

Mesh:

Substances:

Year:  2016        PMID: 27513396     DOI: 10.3906/sag-1504-37

Source DB:  PubMed          Journal:  Turk J Med Sci        ISSN: 1300-0144            Impact factor:   0.973


  3 in total

1.  Effect of hyperbaric oxygen therapy on cognitive dysfunction induced by nitrous oxide abuse: protocol of a randomised, double-blinded, placebo-controlled trial.

Authors:  Dan Luo; Lu Tan; Danling Shen; Mingfeng Lai; Qiao Tang; Jiajun Xu; Jing Li
Journal:  BMJ Open       Date:  2022-04-22       Impact factor: 3.006

2.  Physiological Effects, Psychomotor Analysis, Cognition, and Recovery Pattern in Children Undergoing Primary Molar Extractions under Nitrous Oxide Sedation Using Two Different Induction Techniques: A Split-mouth Randomized Controlled Clinical Trial.

Authors:  Vineet Khinda; Dinesh Rao; Surender Ps Sodhi; Gurlal S Brar; Nikhil Marwah
Journal:  Int J Clin Pediatr Dent       Date:  2021

3.  Hyperbaric oxygen therapy to improve cognitive dysfunction and encephalatrophy induced by N2O for recreational use: a case report.

Authors:  Dan Luo; Jiajun Xu; Li Hu; Liangming Yu; Leling Xie; Jing Li
Journal:  Neuropsychiatr Dis Treat       Date:  2018-08-03       Impact factor: 2.570

  3 in total

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