Literature DB >> 27512438

Successful pregnancy outcome in a woman with Turner's syndrome.

E Church1, A Bellis1, I O'Connell1, N Naqvi1.   

Abstract

Women with Turner's syndrome have a high incidence of cardiovascular complications, endocrine and hypertensive disorders. Those with the 45X chromosome complement require oocyte donation and in vitro fertilisation to conceive. Pregnancies in such women are challenging to manage due to the high risk of pregnancy-related hypertensive disorders, impaired glucose tolerance, fetal growth restriction and preterm birth. Women also need to be aware of the significant risk of aortic dilatation, dissection or rupture in pregnancy, which may be fatal. Despite these risks, favourable obstetric outcomes are achievable with careful pre-pregnancy counselling and cardiovascular assessment, intensive multidisciplinary antenatal monitoring and individualised delivery planning. We report the case of a 33-year-old woman with Turner's syndrome, pre-existing hypertension, insulin-dependent diabetes and primary hypoparathyroidism who had a successful pregnancy with good maternal and fetal outcomes despite the complexity of her medical conditions.

Entities:  

Keywords:  High-risk pregnancy; Turner's syndrome; diabetes; hypertension; infertility

Year:  2014        PMID: 27512438      PMCID: PMC4934975          DOI: 10.1177/1753495X14532635

Source DB:  PubMed          Journal:  Obstet Med        ISSN: 1753-495X


  14 in total

1.  Turner's syndrome and pregnancies after oocyte donation.

Authors:  T Foudila; V Söderström-Anttila; O Hovatta
Journal:  Hum Reprod       Date:  1999-02       Impact factor: 6.918

Review 2.  A successful pregnancy in a Turner syndrome with oocyte donation.

Authors:  E C Nwosu; A Brockbank; S A Walkinshaw
Journal:  J Obstet Gynaecol       Date:  2012-07       Impact factor: 1.246

Review 3.  Turner's syndrome.

Authors:  P Saenger
Journal:  N Engl J Med       Date:  1996-12-05       Impact factor: 91.245

4.  Classic pages in obstetrics and gynecology by Henry H. Turner. A syndrome of infantilism, congenital webbed neck, and cubitus valgus. Endocrinology, vol. 23, pp. 566-574, 1938.

Authors: 
Journal:  Am J Obstet Gynecol       Date:  1972-05-15       Impact factor: 8.661

Review 5.  Pregnancies in women with Turner's syndrome.

Authors:  O Hovatta
Journal:  Ann Med       Date:  1999-04       Impact factor: 4.709

6.  Moderate aortic enlargement and bicuspid aortic valve are associated with aortic dissection in Turner syndrome: report of the international turner syndrome aortic dissection registry.

Authors:  Misty Carlson; Nathan Airhart; Leo Lopez; Michael Silberbach
Journal:  Circulation       Date:  2012-10-02       Impact factor: 29.690

Review 7.  Dissection of the aorta in Turner syndrome: two cases and review of 85 cases in the literature.

Authors:  M Carlson; M Silberbach
Journal:  J Med Genet       Date:  2007-09-14       Impact factor: 6.318

8.  Careful cardiovascular screening and follow-up of women with Turner syndrome before and during pregnancy is necessary to prevent maternal mortality.

Authors:  Celine Chalas Boissonnas; Celine Davy; Marie Bornes; Leila Arnaout; Christophe Meune; Vassilis Tsatsatris; Alexandre Mignon; Pierre Jouannet
Journal:  Fertil Steril       Date:  2008-11-06       Impact factor: 7.329

9.  Risk of death in pregnancy achieved through oocyte donation in patients with Turner syndrome: a national survey.

Authors:  Megan Freebury Karnis; Alison Elizabeth Zimon; Sasmira Indru Lalwani; Lorna Smink Timmreck; Sigal Klipstein; Richard Henry Reindollar
Journal:  Fertil Steril       Date:  2003-09       Impact factor: 7.329

10.  Determinants of echocardiographic aortic root size. The Framingham Heart Study.

Authors:  R S Vasan; M G Larson; D Levy
Journal:  Circulation       Date:  1995-02-01       Impact factor: 29.690

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.