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Literature DB >> 27511898

Identification of Giardia lamblia Assemblage E in Humans Points to a New Anthropozoonotic Cycle.

Maria Fantinatti¹, Alexandre R Bello², Octavio Fernandes¹, Alda M Da-Cruz³.

Abstract

Giardia lamblia is a pathogen transmitted by water and food that causes infection worldwide. Giardia genotypes are classified into 8 assemblages (A-H). Assemblages A and B are detected in humans, but they are potentially zoonotic because they infect other mammalian hosts. Giardia in samples from 44 children was genotyped. Conserved fragments of the genes encoding β-giardin and glutamate dehydrogenase were sequenced and their alignment were carried out with sequences deposited in GenBank. As expected for Rio de Janeiro, the majority of samples were related to assemblage A. Surprisingly, assemblage E was detected in 15 samples. Detection of assemblage E in humans suggests a new zoonotic route of Giardia transmission.

Entities: Disease Species

Keywords: Giardia lamblia; assemblage E; molecular characterization; β-giardin gene

Mesh：

Substances：

Year: 2016 PMID： 27511898 DOI： 10.1093/infdis/jiw361

Source DB: PubMed Journal: J Infect Dis ISSN： 0022-1899 Impact factor: 5.226

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Cited

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