Literature DB >> 27510716

An Assessment of the State of Current Practice in Coagulation Laboratories.

Nicole D Zantek1, Catherine P Hayward2, Trevor G Simcox3, Kristi J Smock4, Peihong Hsu5, Elizabeth M Van Cott3.   

Abstract

OBJECTIVES: To assess the state of current practice in coagulation laboratories regarding three pressing issues: staffing, handling Ebola specimens, and testing/billing for tests that measure direct oral anticoagulants (DOAC).
METHODS: A survey and analysis of specialized coagulation laboratories in North America was conducted.
RESULTS: Approximately 4,000 special coagulation tests-per-technologist-per-year was rated as either a "good" staffing level or "adequate-but-ideally-need-more" employees. Requiring technologists to perform more than that was rated as an "inadequate" staffing level. For Ebola patients, coagulation testing is mostly performed by point-of-care. Only 26.1% would perform coagulation tests for Ebola specimens within their laboratory (rather than at the bed side or a separate designated space outside the laboratory). Coagulation tests offered for Ebola patients were limited: prothrombin time (63.0% of laboratories), activated partial thromboplastin time (37.0%), D-dimer (13.0%), and fibrinogen (8.7%); 26.1% of laboratories did not offer any coagulation tests for Ebola patients. Approximately 35% of special coagulation laboratories bill for at least one laboratory test for DOACs: 33% bill for an anti-Xa calibrated with rivaroxaban, 17% bill for an anti-Xa calibrated with apixaban, and 27% bill for at least one of several tests for dabigatran. Approximately 48% do not offer any tests for DOACs.
CONCLUSIONS: These results may help laboratories negotiate for additional technologists if needed, prepare for Ebola specimens, and manage the demand for laboratory tests for new DOAC anticoagulants. © American Society for Clinical Pathology, 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Apixaban; Dabigatran; Direct oral anticoagulant (DOAC); Ebola; Rivaroxaban; Specialized coagulation laboratory; Staffing

Mesh:

Year:  2016        PMID: 27510716     DOI: 10.1093/ajcp/aqw121

Source DB:  PubMed          Journal:  Am J Clin Pathol        ISSN: 0002-9173            Impact factor:   2.493


  4 in total

Review 1.  Laboratory Assessment of the Anticoagulant Activity of Direct Oral Anticoagulants: A Systematic Review.

Authors:  Bethany T Samuelson; Adam Cuker; Deborah M Siegal; Mark Crowther; David A Garcia
Journal:  Chest       Date:  2016-09-13       Impact factor: 9.410

2.  Specific Point-of-Care Testing of Coagulation in Patients Treated with Dabigatran.

Authors:  Florian Härtig; Ingvild Birschmann; Andreas Peter; Matthias Ebner; Charlotte Spencer; Michael Gramlich; Hardy Richter; Joachim Kuhn; Rainer Lehmann; Gunnar Blumenstock; Christine S Zuern; Ulf Ziemann; Sven Poli
Journal:  Thromb Haemost       Date:  2021-01-14       Impact factor: 5.249

Review 3.  Recanalisation therapies for acute ischaemic stroke in patients on direct oral anticoagulants.

Authors:  Duncan Wilson; Teddy Y Wu; David J Seiffge; Thomas Meinel; Jan Christoph Purrucker; Johannes Kaesmacher; Urs Fischer
Journal:  J Neurol Neurosurg Psychiatry       Date:  2021-02-04       Impact factor: 10.154

4.  System performance evaluation of the cobas t 711 and cobas t 511 coagulation analyzers in routine laboratory settings.

Authors:  Steve Kitchen; Moniek de Maat; Michael Nagler; Robert Jones; Anna Lowe; John Burden; Kai Groneberg; Gergely Rozsnyai
Journal:  Blood Coagul Fibrinolysis       Date:  2020-10       Impact factor: 1.061

  4 in total

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