Ivana Kovalova1, Milos Kerkovsky, Zdenek Kadanka, Zdenek Kadanka, Martin Nemec, Barbora Jurova, Ladislav Dusek, Jiri Jarkovsky, Josef Bednarik. 1. *Department of Neurology, University Hospital Brno, Brno, Czech Republic †Applied Neurosciences Research Group, Central European Institute of Technology, Masaryk University Brno, Brno, Czech Republic ‡Multimodal and Functional Imaging Laboratory, Central European Institute of Technology, Masaryk University Brno, Brno, Czech Republic §Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic ¶Department of Radiology, University Hospital Brno, Brno, Czech Republic.
Abstract
STUDY DESIGN: Cross-sectional population-based observational study. OBJECTIVE: To estimate the prevalence of nonmyelopathic spondylotic cervical cord compression (NMSCCC) and cervical spondylotic myelopathy (CSM) in a population older than 40 years and to evaluate the magnetic resonance imaging (MRI) characteristics of these conditions. SUMMARY OF BACKGROUND DATA: The prevalence of neither NMSCCC nor CSM is known and there exists no commonly accepted quantitative MRI definition of cervical cord compression. METHODS: A group of 183 randomly recruited volunteers, 93 women, median age 66 years, range 40-80 years, underwent MRI examination of the cervical spine and spinal cord on a 1.5 T device using conventional sequences from disc levels C2/C3 to C6/C7. The imaging criterion for cervical cord compression was defined as a change in spinal cord contour at the level of an intervertebral disc on axial or sagittal MRI scan. RESULTS: MRI signs of cervical cord compression were found in 108 individuals (59.0%; 95% CI: 51.5%-66.2%); their numbers increased with age from 31.6% in the fifth decade to 66.8% in the eighth. Clinical signs of symptomatic CSM were found in two cases (1.1%), and 75 cases (41.0%) were without compression. An anteroposterior cervical canal diameter at the level of intervertebral disc (CDdisc) of less than 9.9 mm was associated with the highest probability of NMSCCC-odds ratio (OR) = 32.5, followed by a compression ratio of ≤0.5: OR = 11.1. CONCLUSION: The prevalence of NMSCCC in a population older than 40 years is higher than previously reported and increases with age. CDdisc and compression ratio had the highest capacity to discriminate between subjects with and without asymptomatic compression, and their cut-off values could be used to objectify criteria for cervical cord compression. LEVEL OF EVIDENCE: 2.
STUDY DESIGN: Cross-sectional population-based observational study. OBJECTIVE: To estimate the prevalence of nonmyelopathic spondylotic cervical cord compression (NMSCCC) and cervical spondylotic myelopathy (CSM) in a population older than 40 years and to evaluate the magnetic resonance imaging (MRI) characteristics of these conditions. SUMMARY OF BACKGROUND DATA: The prevalence of neither NMSCCC nor CSM is known and there exists no commonly accepted quantitative MRI definition of cervical cord compression. METHODS: A group of 183 randomly recruited volunteers, 93 women, median age 66 years, range 40-80 years, underwent MRI examination of the cervical spine and spinal cord on a 1.5 T device using conventional sequences from disc levels C2/C3 to C6/C7. The imaging criterion for cervical cord compression was defined as a change in spinal cord contour at the level of an intervertebral disc on axial or sagittal MRI scan. RESULTS: MRI signs of cervical cord compression were found in 108 individuals (59.0%; 95% CI: 51.5%-66.2%); their numbers increased with age from 31.6% in the fifth decade to 66.8% in the eighth. Clinical signs of symptomatic CSM were found in two cases (1.1%), and 75 cases (41.0%) were without compression. An anteroposterior cervical canal diameter at the level of intervertebral disc (CDdisc) of less than 9.9 mm was associated with the highest probability of NMSCCC-odds ratio (OR) = 32.5, followed by a compression ratio of ≤0.5: OR = 11.1. CONCLUSION: The prevalence of NMSCCC in a population older than 40 years is higher than previously reported and increases with age. CDdisc and compression ratio had the highest capacity to discriminate between subjects with and without asymptomatic compression, and their cut-off values could be used to objectify criteria for cervical cord compression. LEVEL OF EVIDENCE: 2.
Authors: Magda Horáková; Tomáš Horák; Jan Valošek; Tomáš Rohan; Eva Koriťáková; Marek Dostál; Jan Kočica; Tomáš Skutil; Miloš Keřkovský; Zdeněk Kadaňka; Petr Bednařík; Alena Svátková; Petr Hluštík; Josef Bednařík Journal: Quant Imaging Med Surg Date: 2022-04
Authors: Jan Valošek; Petr Bednařík; Miloš Keřkovský; Petr Hluštík; Josef Bednařík; Alena Svatkova Journal: J Clin Med Date: 2022-04-20 Impact factor: 4.964
Authors: Allan R Martin; Benjamin De Leener; Julien Cohen-Adad; David W Cadotte; Aria Nouri; Jefferson R Wilson; Lindsay Tetreault; Adrian P Crawley; David J Mikulis; Howard Ginsberg; Michael G Fehlings Journal: BMJ Open Date: 2018-04-13 Impact factor: 2.692