Literature DB >> 27505314

Pediatric Keratoconus in a Tertiary Referral Center: Incidence, Presentation, Risk Factors, and Treatment.

Sylvain El-Khoury, Youssef Abdelmassih, Adib Hamade, Elise Slim, Carole G Cherfan, Elias Chelala, Jamal Bleik, Elias F Jarade.   

Abstract

PURPOSE: To report the incidence, clinical presentation, risk factors, and treatment outcome of pediatric keratoconus in a tertiary referral eye hospital in Beirut, Lebanon.
METHODS: In this retrospective study, the authors evaluated all patients with keratoconus 14 years or younger newly diagnosed at the Beirut Eye Specialist Hospital, Beirut, Lebanon, between January 2010 and December 2014. The incidence of pediatric keratoconus among all pediatric patients and among patients with keratoconus of all ages was assessed. Patients with pediatric keratoconus were evaluated for keratoconus stage, initial presentation, uncorrected distance visual acuity, corrected distance visual acuity (CDVA), corneal topography, and pachymetry. Patients were classified according to different treatment regimen groups and different follow-up visits were evaluated.
RESULTS: During 5 years, 16,808 patients were examined, of whom 2,972 were 14 years or younger. A total of 541 patients were diagnosed as having keratoconus; of those, 16 were 14 years or younger at the time of diagnosis. Hence, the incidence of keratoconus was 0.53% among pediatric patients and 3.78% among adult patients (> 14 years). Initial presentation was during routine checkup (1 of 16) for allergic conjunctivitis (3 of 16), reduced vision (10 of 16), and corneal hydrops (mimicking keratitis) (2 of 16). Except for 2 patients lost to follow-up, all eyes received corneal cross-linking treatment and 16 eyes received additional intracorneal ring segment implantation.
CONCLUSIONS: The incidence of pediatric keratoconus indicates that increased awareness for keratoconus among children is needed, mainly in cases of family history of keratoconus, ocular allergy/pruritus, poor CDVA, corneal hydrops, and/or high astigmatism. [J Refract Surg. 2016;32(8):534-541.]. Copyright 2016, SLACK Incorporated.

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Year:  2016        PMID: 27505314     DOI: 10.3928/1081597X-20160513-01

Source DB:  PubMed          Journal:  J Refract Surg        ISSN: 1081-597X            Impact factor:   3.573


  11 in total

Review 1.  Corneal Cross-Linking for Pediatric Keratcoconus Review.

Authors:  Claudia Perez-Straziota; Ronald N Gaster; Yaron S Rabinowitz
Journal:  Cornea       Date:  2018-06       Impact factor: 2.651

2.  Intrastromal Corneal Ring Segments Implantation And Corneal Cross-Linking For Keratoconus In Children With Vernal Keratoconjunctivitis - Three-Year Results.

Authors:  Mortada Ahmed Abozaid; Amin Abo-Ali Hassan; Abdelsalam Abdalla
Journal:  Clin Ophthalmol       Date:  2019-11-05

3.  Prevalence of Subclinical Keratoconus Among Pediatric Egyptian Population with Astigmatism.

Authors:  Mohamed Karim Sidky; Dina Hosameldin Hassanein; Sherif A Eissa; Yehia M Salah; Nancy M Lotfy
Journal:  Clin Ophthalmol       Date:  2020-03-23

4.  One-year follow-up of accelerated transepithelial corneal collagen cross-linking for progressive pediatric keratoconus.

Authors:  Mi Tian; Weijun Jian; Ling Sun; Yang Shen; Xiaoyu Zhang; Xingtao Zhou
Journal:  BMC Ophthalmol       Date:  2018-03-09       Impact factor: 2.209

5.  The Effect of Age on Corneal Topographic Indices, Keratometry and Visual Acuity After Combined Intrastromal Corneal Ring Segment (ICRS) Implantation and Corneal Crosslinking.

Authors:  Sylvain El-Khoury; Youssef Abdelmassih; Mazen Amro; Ali Dirani; Carol Cherfan; Elias Jarade
Journal:  Med Hypothesis Discov Innov Ophthalmol       Date:  2020-03-30

6.  The prevalence of corneal abnormalities in first-degree relatives of patients with keratoconus: a prospective case-control study.

Authors:  Einat Shneor; Joseph Frucht-Pery; Edna Granit; Ariela Gordon-Shaag
Journal:  Ophthalmic Physiol Opt       Date:  2020-07       Impact factor: 3.117

7.  Intracorneal Ring Segment Implantation for the Management of Keratoconus in Children.

Authors:  Pablo Larco; Pablo Larco; Daniel Torres; David P Piñero
Journal:  Vision (Basel)       Date:  2020-12-23

8.  Corneal Scheimpflug topography values to distinguish between normal eyes, ocular allergy, and keratoconus in children.

Authors:  Matheus Ivan Schmitz Vieira; Alessandro Adad Jammal; Carlos Eduardo Leite Arieta; Monica Alves; Jose Paulo Cabral de Vasconcellos
Journal:  Sci Rep       Date:  2021-12-20       Impact factor: 4.379

9.  Allergen-specific exposure associated with high immunoglobulin E and eye rubbing predisposes to progression of keratoconus.

Authors:  Rohit Shetty; Shraddha Sureka; Pallak Kusumgar; Swaminathan Sethu; Kanchan Sainani
Journal:  Indian J Ophthalmol       Date:  2017-05       Impact factor: 1.848

10.  A Case of Early Keratoconus Associated with Eye Rubbing in a Young Child.

Authors:  Victoria Dimacali; Miltos Balidis; Aspasia Adamopoulou; Athina Kozei; Nikolaos Kozeis
Journal:  Ophthalmol Ther       Date:  2020-06-15
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