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Literature DB >> 27504388

Rising Trend of Use of Antidepressants Induced Non- Puerperal Lactation: A Case Report.

Prerna Kukreti¹, Wazid Ali², R C Jiloha³.

Abstract

Non puerperal lactation or galactorrhea is a well known side effect of antipsychotic drugs but has been infrequently described with the use of antidepressants. In past few decades, there have been emerging trend of isolated case reports of selective serotonin reuptake inhibitors induced non puerperal lactation. We report a case of non puerperal lactation following usage of second generation tricyclic antidepressant, nortriptyline and resolution on withdrawing the drug. Literature review has been done for antidepressant induced galactorrhea to understand the current trends, putative mechanism as different from one implicated for antipsychotics and its clinical utility.

Entities: Chemical Disease

Keywords: Galactorrhea; Nortriptyline; Tricyclic antidepressants

Year: 2016 PMID： 27504388 PMCID： PMC4963748 DOI： 10.7860/JCDR/2016/19266.7928

Source DB: PubMed Journal: J Clin Diagn Res ISSN： 0973-709X

14 in total

Review 1. Evaluation and treatment of galactorrhea.

Authors: K S Peña; J A Rosenfeld
Journal: Am Fam Physician Date: 2001-05-01 Impact factor: 3.292

2. Duloxetine-related galactorrhea and restless legs syndrome: a case report.

Authors: Hasan Belli; Mahir Akbudak; Cenk Ural
Journal: Psychiatr Danub Date: 2013-09 Impact factor: 1.063

3. Non-puerperal lactation associated with antidepressant drug use.

Authors: A C Egberts; R H Meyboom; F H De Koning; A Bakker; H G Leufkens
Journal: Br J Clin Pharmacol Date: 1997-09 Impact factor: 4.335

4. Reduced brain norepinephrine and dopamine release in treatment-refractory depressive illness: evidence in support of the catecholamine hypothesis of mood disorders.

Authors: G Lambert; M Johansson; H Agren; P Friberg
Journal: Arch Gen Psychiatry Date: 2000-08

5. A case of paroxetine-induced galactorrhoea with normal serum prolactin level.

Authors: Suddhendu Chakraborty; Debasish Sanyal; Ranjan Bhattacharyya; Subhendu Dutta
Journal: Indian J Pharmacol Date: 2010-10 Impact factor: 1.200

Review 6. A new logical insight and putative mechanism behind fluoxetine-induced amenorrhea, hyperprolactinemia and galactorrhea in a case series.

Authors: Somnath Mondal; Indranil Saha; Saibal Das; Abhrajit Ganguly; Debasis Das; Santanu Kumar Tripathi
Journal: Ther Adv Psychopharmacol Date: 2013-12

Rising Trend of Use of Antidepressants Induced Non- Puerperal Lactation: A Case Report.

Review 1. Evaluation and treatment of galactorrhea.

2. Duloxetine-related galactorrhea and restless legs syndrome: a case report.

3. Non-puerperal lactation associated with antidepressant drug use.

4. Reduced brain norepinephrine and dopamine release in treatment-refractory depressive illness: evidence in support of the catecholamine hypothesis of mood disorders.

5. A case of paroxetine-induced galactorrhoea with normal serum prolactin level.

Review 6. A new logical insight and putative mechanism behind fluoxetine-induced amenorrhea, hyperprolactinemia and galactorrhea in a case series.

Review 7. Sertraline-induced galactorrhea: case report and review of cases reported with other SSRIs.

8. A case with euprolactinemic galactorrhea induced by escitalopram.

Review 9. Extrapyramidal symptoms with selective serotonin reuptake inhibitors.

Review 10. Psychoneuroendocrinology of depression. Prolactin.

1. Galactorrhea during antipsychotic treatment: results from AMSP, a drug surveillance program, between 1993 and 2015.