Literature DB >> 27502930

Etiology and clinical features of 229 cases of bloodstream infection among Chinese HIV/AIDS patients: a retrospective cross-sectional study.

T Qi1, R Zhang1, Y Shen1, L Liu1, D Lowrie1, W Song1, J Chen1, Z Wang1, J Shen1, R Cai1, L Guan1, B Luo1, Y Tang1, H Lu2.   

Abstract

Bloodstream infections (BSIs) are prevalent among people living with HIV/AIDS. The etiology varies in different regions and different periods. We aimed to survey the etiological and clinical features of BSIs in HIV patients in mainland China. We assessed all HIV patients with a positive blood culture in a Chinese teaching hospital from September 2009 through December 2014. We excluded those with specimens likely to have been contaminated. We used Pearson's chi-squared test to measure the differences in characteristics among subgroups of different pathogens. Among 2442 Chinese HIV-seropositive inpatients, 229 (9.38 %) experienced BSIs. The most common pathogens detected included Cryptococcus neoformans (22.7 %), Penicillium marneffei (18.8 %), Mycobacterium tuberculosis (15.3 %), and non-tuberculous mycobacterium (14.8 %). 30/229 (13.1 %) HIV patients with BSIs had a poor prognosis. BSIs are prevalent in hospitalized patients with HIV/AIDS in China. Fungi and mycobacteria are the predominant pathogens.

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Year:  2016        PMID: 27502930     DOI: 10.1007/s10096-016-2724-7

Source DB:  PubMed          Journal:  Eur J Clin Microbiol Infect Dis        ISSN: 0934-9723            Impact factor:   3.267


  16 in total

1.  Epidemiology of bloodstream infections and predictive factors of mortality among HIV-infected adult patients in Thailand in the era of highly active antiretroviral therapy.

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Journal:  Jpn J Infect Dis       Date:  2012       Impact factor: 1.362

2.  Community-acquired septicaemia in southern Viet Nam: the importance of multidrug-resistant Salmonella typhi.

Authors:  N T Hoa; T S Diep; J Wain; C M Parry; T T Hien; M D Smith; A L Walsh; N J White
Journal:  Trans R Soc Trop Med Hyg       Date:  1998 Sep-Oct       Impact factor: 2.184

3.  Species distribution in human immunodeficiency virus-related mycobacterial infections: implications for selection of initial treatment.

Authors:  V Montessori; P Phillips; J Montaner; L Haley; K Craib; E Bessuille; W Black
Journal:  Clin Infect Dis       Date:  1996-06       Impact factor: 9.079

4.  Utility of blood cultures and incidence of mycobacteremia in patients with suspected tuberculosis in a South African infectious disease referral hospital.

Authors:  A von Gottberg; L Sacks; S Machala; L Blumberg
Journal:  Int J Tuberc Lung Dis       Date:  2001-01       Impact factor: 2.373

5.  Simple and rapid identification of the Mycobacterium tuberculosis complex by immunochromatographic assay using anti-MPB64 monoclonal antibodies.

Authors:  C Abe; K Hirano; T Tomiyama
Journal:  J Clin Microbiol       Date:  1999-11       Impact factor: 5.948

6.  Bacteremic disseminated tuberculosis in sub-saharan Africa: a prospective cohort study.

Authors:  John A Crump; Habib O Ramadhani; Anne B Morrissey; Wilbrod Saganda; Mtumwa S Mwako; Lan-Yan Yang; Shein-Chung Chow; Boniface N Njau; Godfrey S Mushi; Venance P Maro; L Barth Reller; John A Bartlett
Journal:  Clin Infect Dis       Date:  2012-04-16       Impact factor: 9.079

7.  Detection of mycobacteria in the bloodstream of patients with acquired immunodeficiency syndrome in a university hospital in Brazil.

Authors:  C P Oplustil; O H Leite; M S Oliveira; S I Sinto; D E Uip; M Boulos; C F Mendes
Journal:  Braz J Infect Dis       Date:  2003-02-21       Impact factor: 1.949

Review 8.  Community-acquired bloodstream infections in Africa: a systematic review and meta-analysis.

Authors:  Elizabeth A Reddy; Andrea V Shaw; John A Crump
Journal:  Lancet Infect Dis       Date:  2010-06       Impact factor: 25.071

9.  Bloodstream infections among human immunodeficiency virus-infected adult patients: epidemiology and risk factors for mortality.

Authors:  M Ortega; M Almela; A Soriano; F Marco; J A Martínez; A Muñoz; G Peñarroja; J Mensa
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2008-05-01       Impact factor: 3.267

10.  Penicillium marneffei infection: an emerging disease in mainland China.

Authors:  Yongxuan Hu; Junmin Zhang; Xiqing Li; Yabo Yang; Yong Zhang; Jianchi Ma; Liyan Xi
Journal:  Mycopathologia       Date:  2012-09-17       Impact factor: 2.574

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  4 in total

1.  Burden of Talaromyces marneffei infection in people living with HIV/AIDS in Asia during ART era: a systematic review and meta-analysis.

Authors:  Yuanyuan Qin; Xiaojie Huang; Hui Chen; Xinchao Liu; Yao Li; Jianhua Hou; Aixin Li; Xiaofeng Yan; Yaokai Chen
Journal:  BMC Infect Dis       Date:  2020-07-29       Impact factor: 3.090

2.  Talaromyces marneffei is the Persistent Overwhelming Bloodstream Infection Pathogen Among HIV Inpatients in Fujian, China.

Authors:  Jinglan Lai; Yuming Liu; Hanhui Ye; Yahong Chen
Journal:  Infect Drug Resist       Date:  2022-09-05       Impact factor: 4.177

3.  Clinical characteristics and risk factors for poor prognosis among HIV patients with Talaromyces marneffei bloodstream infection.

Authors:  Jianjun Sun; Weiwei Sun; Yang Tang; Renfang Zhang; Li Liu; Yinzhong Shen; Jiangrong Wang; Jun Chen; Tangkai Qi; Zhenyan Wang; Wei Song; Yixiao Lin; Shuibao Xu; Hongzhou Lu
Journal:  BMC Infect Dis       Date:  2021-06-01       Impact factor: 3.090

4.  Cost-Effectiveness of Amphotericin B Deoxycholate Versus Itraconazole for Induction Therapy of Talaromycosis in Human Immunodeficiency Virus-Infected Adults in Vietnam.

Authors:  James Buchanan; James Altunkaya; Nguyen Van Kinh; Nguyen Van Vinh Chau; Vo Trieu Ly; Pham Thi Thanh Thuy; Vu Hai Vinh; Doan Thi Hong Hanh; Nguyen Thuy Hang; Tran Phuong Thuy; Rogier van Doorn; Guy Thwaites; Alastair Gray; Thuy Le
Journal:  Open Forum Infect Dis       Date:  2021-07-05       Impact factor: 3.835

  4 in total

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