Literature DB >> 27500248

Successful Kidney and Lung Transplantation From a Deceased Donor With Blunt Abdominal Trauma and Intestinal Perforation.

Tim C van Smaalen1, Christina Krikke2, Jan Willem Haveman2, L W Ernest van Heurn3.   

Abstract

The number of organ donors is limited by many contraindications for donation and poor quality of potential organ donors. Abdominal infection is a generally accepted contraindication for donation of abdominal organs. We present a 43-year-old man with lethal brain injury, blunt abdominal trauma, and intestinal perforation. After withdrawal of life-sustaining treatment and circulatory arrest, a minilaparotomy confirmed abdominal contamination with intestinal content. After closure of the abdomen, organs were preserved with in situ preservation with an aortic cannula inserted via the femoral artery. Thereafter, the kidneys were procured via bilateral lumbotomy to reduce the risk of direct bacterial contamination; lungs were retrieved following a standard practice. There was no bacterial or fungal growth in the machine preservation fluid of both kidneys. All organs were successfully transplanted, without postoperative infection, and functioned well after 6 months. We hereby show that direct contamination of organs can be avoided with the use of in situ preservation and retroperitoneal procurement. Intestinal perforation is not an absolute contraindication for donation, although the risk of bacterial or fungal transmission has to be evaluated per case.

Entities:  

Year:  2015        PMID: 27500248      PMCID: PMC4946498          DOI: 10.1097/TXD.0000000000000572

Source DB:  PubMed          Journal:  Transplant Direct        ISSN: 2373-8731


  27 in total

1.  Outcome of transplantation of organs procured from bacteremic donors.

Authors:  R B Freeman; I Giatras; M E Falagas; S Supran; K O'Connor; J Bradley; D R Snydman; F L Delmonico
Journal:  Transplantation       Date:  1999-10-27       Impact factor: 4.939

Review 2.  MDCT in blunt intestinal trauma.

Authors:  Stefania Romano; Mariano Scaglione; Giovanni Tortora; Antonio Martino; Francesco Di Pietto; Luigia Romano; Roberto Grassi
Journal:  Eur J Radiol       Date:  2006-06-23       Impact factor: 3.528

3.  Quality and safety in the Italian donor evaluation process.

Authors:  Alessandro Nanni Costa; Paolo Grossi; Andrea Gianelli Castiglione; Walter F Grigioni
Journal:  Transplantation       Date:  2008-04-27       Impact factor: 4.939

4.  Candida vascular complication in a liver transplant recipient due to yeast contamination of preservation solution.

Authors:  E Levesque; G Suet; J C Merle; P Compagnon; R Amathieu; C Feray; F Botterel; F Foulet; D Azoulay; G Dhonneur
Journal:  Transpl Infect Dis       Date:  2014-07-01       Impact factor: 2.228

5.  Kidneys from donors after cardiac death provide survival benefit.

Authors:  Maarten G Snoeijs; Douglas E Schaubel; Ronald Hené; Andries J Hoitsma; Mirza M Idu; Jan N Ijzermans; Rutger J Ploeg; Jan Ringers; Maarten H Christiaans; Wim A Buurman; L W Ernest van Heurn
Journal:  J Am Soc Nephrol       Date:  2010-05-20       Impact factor: 10.121

6.  Multidetector CT findings of bowel transection in blunt abdominal trauma.

Authors:  Hyun Suk Cho; Ji Young Woo; Hye-Suk Hong; Mee Hyun Park; Hong Il Ha; Ik Yang; Yul Lee; Ah Young Jung; Ji-Young Hwang
Journal:  Korean J Radiol       Date:  2013-07-17       Impact factor: 3.500

7.  Donor-derived fungal infections in organ transplant recipients: guidelines of the American Society of Transplantation, infectious diseases community of practice.

Authors:  N Singh; S Huprikar; S D Burdette; M I Morris; J E Blair; L J Wheat
Journal:  Am J Transplant       Date:  2012-06-13       Impact factor: 8.086

8.  Outcome of renal transplantation in eight patients with Candida sp. contamination of preservation fluid.

Authors:  M Matignon; F Botterel; V Audard; B Dunogue; K Dahan; P Lang; S Bretagne; P Grimbert
Journal:  Am J Transplant       Date:  2008-03       Impact factor: 8.086

9.  ASTS recommended practice guidelines for controlled donation after cardiac death organ procurement and transplantation.

Authors:  D J Reich; D C Mulligan; P L Abt; T L Pruett; M M I Abecassis; A D'Alessandro; E A Pomfret; R B Freeman; J F Markmann; D W Hanto; A J Matas; J P Roberts; R M Merion; G B G Klintmalm
Journal:  Am J Transplant       Date:  2009-07-16       Impact factor: 8.086

10.  Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America.

Authors:  Joseph S Solomkin; John E Mazuski; John S Bradley; Keith A Rodvold; Ellie J C Goldstein; Ellen J Baron; Patrick J O'Neill; Anthony W Chow; E Patchen Dellinger; Soumitra R Eachempati; Sherwood Gorbach; Mary Hilfiker; Addison K May; Avery B Nathens; Robert G Sawyer; John G Bartlett
Journal:  Surg Infect (Larchmt)       Date:  2010-02       Impact factor: 2.150

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