María Perales1, Alejandro Santos-Lozano2, Fabian Sanchis-Gomar3, María Luaces4, Helios Pareja-Galeano5, Nuria Garatachea6, Rubén Barakat7, Alejandro Lucia5. 1. Research Institute, Hospital 12 de Octubre ('i+12'), Madrid, Spain;; Camilo Jose Cela University, Madrid, Spain; 2. Research Institute, Hospital 12 de Octubre ('i+12'), Madrid, Spain;; GIDFYS, Department of Health Sciences, European University Miguel de Cervantes, Valladolid, Spain; 3. Research Institute, Hospital 12 de Octubre ('i+12'), Madrid, Spain ; 4. Hospital Clínico San Carlos, Madrid, Spain ; 5. Research Institute, Hospital 12 de Octubre ('i+12'), Madrid, Spain;; European University, Madrid, Spain; 6. Research Institute, Hospital 12 de Octubre ('i+12'), Madrid, Spain;; Facultad de Ciencias de la Salud y del Deporte, GENUD (Growth, Exercise, Nutrition and Development) Research Group, Instituto Agroalimentario de Aragón -IA2- (Universidad de Zaragoza-CITA), Zaragoza, Spain; 7. AFIPE Research Group, Technical University of Madrid, Madrid, Spain.
Abstract
BACKGROUND: Scarce evidence is available on the potential cardiovascular abnormalities associated with some common gestational complications. We aimed to analyze the potential maternal cardiac alterations related to gestational complications, including body mass index (BMI) >25 kg/m(2), gaining excessive weight, or developing antenatal depression. METHODS: The design of this study was a secondary analysis of a randomized controlled trial. Echocardiography was performed to assess cardiovascular indicators of maternal hemodynamic, cardiac remodeling and left ventricular (LV) function in 59 sedentary pregnant women at 20 and 34 weeks of gestation. RESULTS: Starting pregnancy with a BMI >25 kg/m(2), gaining excessive weight, and developing antenatal depression had no cardiovascular impact on maternal health (P value >0.002). Depressed women were more likely to exceed weight gain recommendations than non-depressed women (P value <0.002). CONCLUSIONS: The evaluated gestational complications seem not to induce cardiovascular alterations in hemodynamic, remodeling and LV function indicators. However, developing antenatal depression increases the risk of an excessive weight gain. This finding is potentially important because excessive weight gain during pregnancy associates with a higher risk of cardiovascular diseases (CVD) later in life.
RCT Entities:
BACKGROUND: Scarce evidence is available on the potential cardiovascular abnormalities associated with some common gestational complications. We aimed to analyze the potential maternal cardiac alterations related to gestational complications, including body mass index (BMI) >25 kg/m(2), gaining excessive weight, or developing antenatal depression. METHODS: The design of this study was a secondary analysis of a randomized controlled trial. Echocardiography was performed to assess cardiovascular indicators of maternal hemodynamic, cardiac remodeling and left ventricular (LV) function in 59 sedentary pregnant women at 20 and 34 weeks of gestation. RESULTS: Starting pregnancy with a BMI >25 kg/m(2), gaining excessive weight, and developing antenatal depression had no cardiovascular impact on maternal health (P value >0.002). Depressed women were more likely to exceed weight gain recommendations than non-depressed women (P value <0.002). CONCLUSIONS: The evaluated gestational complications seem not to induce cardiovascular alterations in hemodynamic, remodeling and LV function indicators. However, developing antenatal depression increases the risk of an excessive weight gain. This finding is potentially important because excessive weight gain during pregnancy associates with a higher risk of cardiovascular diseases (CVD) later in life.
Authors: H Valensise; G P Novelli; B Vasapollo; G Di Ruzza; M E Romanini; M Marchei; G Larciprete; D Manfellotto; C Romanini; A Galante Journal: Hypertension Date: 2001-05 Impact factor: 10.190
Authors: Gian Paolo Novelli; Herbert Valensise; Barbara Vasapollo; Giovanni Larciprete; Giuseppe Di Pierro; Francesco Altomare; Domenico Arduini; Alberto Galante Journal: Hypertens Pregnancy Date: 2003 Impact factor: 2.108
Authors: Morgana L Mongraw-Chaffin; Cheryl A M Anderson; Jeanne M Clark; Wendy L Bennett Journal: Obesity (Silver Spring) Date: 2013-12-04 Impact factor: 5.002