| Literature DB >> 27498975 |
Carlos Hernán Rodríguez1, Norah Balderrama Yarhui1, Marcela Nastro1, Tamara Nuñez Quezada2, Glenda Castro Cañarte3, Raquel Magne Ventura4, Tayita Ugarte Cuba5, Natalia Valenzuela6, Freddy Roach6, María Inés Mota7, Noelia Burger7, Gladys Velázquez Aguayo8, Juana Ortellado-Canese8, Geni Bruni9, Cecilia Pandolfo9, Nadya Bastyas9, Angela Famiglietti1.
Abstract
One hundred and twenty-six epidemiologically sequential, unrelated, carbapenem-resistant Acinetobacter baumannii isolates from nine hospitals in six countries of South America were collected between July 2013 and June 2014. Genes coding for Ambler class D and B carbapenemases were sought by PCR. All isolates were typed using the 3-locus sequence typing and blaOXA-51-like sequence-based typing techniques. The blaOXA-23 gene was recovered in all the participating hospitals and in all the isolates of seven of nine medical centres. The blaOXA-72 gene was only recovered in the two medical centres from Guayaquil city, Ecuador. Trilocus sequence typing revealed the presence of sequence groups SG2, SG4 and SG5. blaOXA-51-like sequence-based typing revealed the presence of blaOXA-132, blaOXA-65, blaOXA-69 and blaOXA-64. Our results showed that the population of carbapenem-resistant A. baumannii in South America was principally associated with ST79, ST25 and ST15 (92 %) and harboured the blaOXA-23 gene mainly. CC2 was not detected.Entities:
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Year: 2016 PMID： 27498975 DOI： 10.1099/jmm.0.000328
Source DB: PubMed Journal: J Med Microbiol ISSN： 0022-2615 Impact factor: 2.472