Literature DB >> 27498202

Management of locoregional recurrence in cutaneous squamous cell carcinoma of the head and neck.

Ulrich Strassen1, Benedikt Hofauer2, Christian Jacobi3, Andreas Knopf2.   

Abstract

Cutaneous squamous cell carcinomas often affect elderly patients. Follow-up monitoring is difficult in these patients due to their multi-morbidity and reduced compliance. Tumour recurrence is consequently diagnosed in advanced tumour stages. Surgical therapy with curative intention often requires extended resections. The study at hand should determine whether surgical concepts are warranted in this collective. Sixty-seven patients who underwent surgical procedure due to recurrent disease of cutaneous head and neck squamous cell carcinoma were included. The cohort was divided in patients with/without adjuvant therapeutic regimens. Data were assessed retrospectively. Complete tumour resection was achieved in 85 % of our patients. Patients with adjuvant treatment demonstrated a favorable 5-year-recurrence-free interval (78 vs 30 %) and overall survival (79 vs 46 %). Complete surgical resection of advanced recurrent head and neck cutaneous squamous cell carcinomas is possible and yields favorable results in terms of survival, especially if combined with adjuvant treatment.

Entities:  

Keywords:  Cutaneous squamous cell carcinoma; Head and neck; Outcome; Recurrence; Therapy

Mesh:

Year:  2016        PMID: 27498202     DOI: 10.1007/s00405-016-4243-7

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  17 in total

1.  Squamous Cell Carcinoma of the Skin has More Than Doubled Over the Last Decade in the UK.

Authors:  Peter K C Goon; David C Greenberg; Laszlo Igali; Nick J Levell
Journal:  Acta Derm Venereol       Date:  2016-08-23       Impact factor: 4.437

Review 2.  Chemotherapy advances in locally advanced head and neck cancer.

Authors:  Peter Georges; Kumar Rajagopalan; Chady Leon; Priya Singh; Nadir Ahmad; Kamyar Nader; Gregory J Kubicek
Journal:  World J Clin Oncol       Date:  2014-12-10

3.  Prediction score for lymph node metastasis from cutaneous squamous cell carcinoma of the external ear.

Authors:  K Wermker; J Kluwig; S Schipmann; M Klein; H J Schulze; C Hallermann
Journal:  Eur J Surg Oncol       Date:  2014-08-20       Impact factor: 4.424

4.  Lymph Node Metastasis in Cutaneous Head and Neck Squamous Cell Carcinoma.

Authors:  Eldad Silberstein; Efrat Sofrin; Alexander Bogdanov-Berezovsky; Michael Nash; Nili Segal
Journal:  Dermatol Surg       Date:  2015-10       Impact factor: 3.398

Review 5.  Nonmelanoma Cutaneous Head and Neck Cancer and Merkel Cell Carcinoma: Current Concepts, Advances, and Controversies.

Authors:  Sandro V Porceddu; Michael J Veness; Alexander Guminski
Journal:  J Clin Oncol       Date:  2015-09-08       Impact factor: 44.544

6.  Outcomes after surgery and postoperative radiotherapy for perineural spread of head and neck cutaneous squamous cell carcinoma.

Authors:  Timothy A Warren; Benedict Panizza; Sandro V Porceddu; Mitesh Gandhi; Parag Patel; Martin Wood; Christina M Nagle; Michael Redmond
Journal:  Head Neck       Date:  2015-05-06       Impact factor: 3.147

Review 7.  Melanotic and non-melanotic malignancies of the face and external ear - A review of current treatment concepts and future options.

Authors:  Andreas Kolk; Klaus-Dietrich Wolff; Ralf Smeets; Marco Kesting; Rüdiger Hein; Alexander W Eckert
Journal:  Cancer Treat Rev       Date:  2014-04-16       Impact factor: 12.111

Review 8.  Diagnosis and treatment of invasive squamous cell carcinoma of the skin: European consensus-based interdisciplinary guideline.

Authors:  Alexander Stratigos; Claus Garbe; Celeste Lebbe; Josep Malvehy; Veronique del Marmol; Hubert Pehamberger; Ketty Peris; Jürgen C Becker; Iris Zalaudek; Philippe Saiag; Mark R Middleton; Lars Bastholt; Alessandro Testori; Jean-Jacques Grob
Journal:  Eur J Cancer       Date:  2015-07-25       Impact factor: 9.162

9.  Evaluation of the definitions of "high-risk" cutaneous squamous cell carcinoma using the american joint committee on cancer staging criteria and national comprehensive cancer network guidelines.

Authors:  Melinda B Chu; Jordan B Slutsky; Maulik M Dhandha; Brandon T Beal; Eric S Armbrecht; Ronald J Walker; Mark A Varvares; Scott W Fosko
Journal:  J Skin Cancer       Date:  2014-09-17

10.  Analysis of selected risk factors for nodal metastases in head and neck cutaneous squamous cell carcinoma.

Authors:  Mateusz Szewczyk; Jakub Pazdrowski; Paweł Golusiński; Aleksandra Dańczak-Pazdrowska; Sławomir Marszałek; Wojciech Golusiński
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-09-13       Impact factor: 2.503

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  2 in total

1.  Evidence-Based Consensus Recommendations for the Evolving Treatment of Patients with High-Risk and Advanced Cutaneous Squamous Cell Carcinoma.

Authors:  Guilherme Rabinowits; Michael R Migden; Todd E Schlesinger; Robert L Ferris; Morganna Freeman; Valerie Guild; Shlomo Koyfman; Anna C Pavlick; Neil Swanson; Gregory T Wolf; Scott M Dinehart
Journal:  JID Innov       Date:  2021-08-25

Review 2.  Skin Cancer Epidemics in the Elderly as An Emerging Issue in Geriatric Oncology.

Authors:  Simone Garcovich; Giuseppe Colloca; Pietro Sollena; Bellieni Andrea; Lodovico Balducci; William C Cho; Roberto Bernabei; Ketty Peris
Journal:  Aging Dis       Date:  2017-10-01       Impact factor: 6.745

  2 in total

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