| Literature DB >> 27497223 |
Elisabeth Vogel1, Sabine Krabbe2, Jan Gründemann2, Jaclyn I Wamsteeker Cusulin2, Andreas Lüthi3.
Abstract
Cannabinoid receptor type 1 (CB1R)-expressing CCK interneurons are key regulators of cortical circuits. Here we report that retrograde endocannabinoid signaling and CB1R-mediated regulation of inhibitory synaptic transmission onto basal amygdala principal neurons strongly depend on principal neuron projection target. Projection-specific asymmetries in the regulation of local inhibitory micro-circuits may contribute to the selective activation of distinct amygdala output pathways during behavioral changes.Entities:
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Year: 2016 PMID: 27497223 DOI: 10.1016/j.neuron.2016.06.036
Source DB: PubMed Journal: Neuron ISSN: 0896-6273 Impact factor: 17.173