Eric C Ehman1, Andrew S Phelps2, Michael A Ohliger3, Sue J Rhee4, John D MacKenzie5, Jesse L Courtier6. 1. Department of Radiology and Biomedical Imaging, UCSF, 505 Parnassus Ave., San Francisco, CA 94143-0628. Electronic address: eric.ehman@ucsf.edu. 2. Department of Radiology and Biomedical Imaging, UCSF Benioff Children's Hospital, 1975 4th Street, CL1578L, San Francisco, CA 94158. Electronic address: andrew.phelps@ucsf.edu. 3. Department of Radiology and Biomedical Imaging, UCSF, 505 Parnassus Ave., San Francisco, CA 94143-0628. Electronic address: michael.ohliger@ucsf.edu. 4. Department of Pediatrics, Division of Ped. Gastroenterology, UCSF Benioff Children's Hospital, Box 0136, 550 16th Street, San Francisco, CA 94134. Electronic address: sue.rhee@ucsf.edu. 5. Department of Radiology and Biomedical Imaging, UCSF Benioff Children's Hospital, 1975 4th Street, CL1578L, San Francisco, CA 94158. Electronic address: john.mackenzie@ucsf.edu. 6. Department of Radiology and Biomedical Imaging, UCSF Benioff Children's Hospital, 1975 4th Street, CL1578L, San Francisco, CA 94158. Electronic address: jesse.courtier@ucsf.edu.
Abstract
PURPOSE: To evaluate the fused, colorized diffusion weighted imaging (DWI) and anatomic T2 images compared to routine contrast-enhanced T1 images at pediatric magnetic resonance enterography (MRE). METHODS: Fused, colorized DWI/T2 images were created from patients with magnetic resonance enterography (MRE) and colonoscopy/biopsy. Radiologists noted inflammation in five bowel segments (terminal ileum-rectosigmoid colon) on postcontrast images and DWI/T2 images. Test characteristics and agreement were calculated. RESULTS: For 20 patients, sensitivity/specificity/positive predictive value (PPV)/negative predictive value (NPV) were 0.53/0.90/0.77/0.76 for DWI/T2 and 0.45/0.90/0.72/0.73 for postcontrast images. Intraobserver agreement was ҡ=0.45-0.73. Interobserver agreement was ҡ=0.53 for DWI/T2 and ҡ=0.63 for postcontrast images. CONCLUSION: DWI/T2 images are similar in sensitivity/specificity to contrast-enhanced images and with moderate intra/interobserver reliability.
RCT Entities:
PURPOSE: To evaluate the fused, colorized diffusion weighted imaging (DWI) and anatomic T2 images compared to routine contrast-enhanced T1 images at pediatric magnetic resonance enterography (MRE). METHODS: Fused, colorized DWI/T2 images were created from patients with magnetic resonance enterography (MRE) and colonoscopy/biopsy. Radiologists noted inflammation in five bowel segments (terminal ileum-rectosigmoid colon) on postcontrast images and DWI/T2 images. Test characteristics and agreement were calculated. RESULTS: For 20 patients, sensitivity/specificity/positive predictive value (PPV)/negative predictive value (NPV) were 0.53/0.90/0.77/0.76 for DWI/T2 and 0.45/0.90/0.72/0.73 for postcontrast images. Intraobserver agreement was ҡ=0.45-0.73. Interobserver agreement was ҡ=0.53 for DWI/T2 and ҡ=0.63 for postcontrast images. CONCLUSION: DWI/T2 images are similar in sensitivity/specificity to contrast-enhanced images and with moderate intra/interobserver reliability.