Luc M Van Bortel1, Tine De Backer2, Patrick Segers3. 1. Department of Pharmacology, Clinical Pharmacology Unit, Heymans Institute of Pharmacology, Ghent University, Ghent, Belgium. 2. Department of Cardiology, Ghent University Hospital, Ghent, Belgium. 3. iMinds Future Health Department, IBiTech-bioMMeda, Ghent University, Ghent, Belgium.