Literature DB >> 27493842

Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review.

Michael A Galgano1, David J Padalino2, Joseph Fullmer3, Satish Krishnamurthy1.   

Abstract

Pilocytic astrocytomas are histologically benign tumors, generally found in the pediatric population. Onset of symptoms is generally insidious, predominantly stemming from mass effect upon nearby structures. Patients harboring a pilocytic astrocytoma may present with gait disturbance, headaches, cranial nerve deficits, as well as hydrocephalus, depending on the exact location. Although cases of adult pilocytic astrocytomas in the adult population are described, they are quite uncommon. We present a case of an adult female presenting with acute neurological compromise resulting from an acutely hemorrhagic posterior fossa pilocytic astrocytoma. Her initial neurological assessment was consistent with a Glasgow coma scale of 4T, as the patient was experiencing decerebrate posturing. An emergent external ventricular drain was placed in the emergency department for acute hydrocephalus as a temporizing measure, prior to evacuation of the associated subdural and intratumoral hemorrhages, as well as resection of the mass. After a long hospital course and extensive rehabilitation, the patient made a remarkable recovery and eventually gave birth to a child via Caesarean section three years after her initial presentation.

Entities:  

Keywords:  hemorrhagic pilocytic astrocytoma; hemorrhagic tumor; intratumoral hemorrhage; neurological compromise; pilocytic astrocytoma; subdural hematoma; suboccipital craniotomy; tumor resection

Year:  2016        PMID: 27493842      PMCID: PMC4969148          DOI: 10.7759/cureus.510

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  12 in total

Review 1.  Hemorrhagic onset of cerebellar pilocytic astrocytoma in an adult: a case report and review of the literature implying a possible relation of degenerative vascular changes to the massive intratumoral hemorrhage.

Authors:  Shunsuke Shibao; Tokuhiro Kimura; Hikaru Sasaki; Hirokazu Fujiwara; Takenori Akiyama; Mari Ueno; Satoka Shidoh; Kazunari Yoshida
Journal:  Brain Tumor Pathol       Date:  2011-10-19       Impact factor: 3.298

2.  Pilocytic astrocytoma with spontaneous intracranial hemorrhages in an elderly adult.

Authors:  Mark K Lyons
Journal:  Clin Neurol Neurosurg       Date:  2006-04-18       Impact factor: 1.876

3.  Subarachnoid hemorrhage from brain tumors in childhood.

Authors:  A Yokota; H Kajiwara; S Matsuoka; M Kohchi; Y Matsukado
Journal:  Childs Nerv Syst       Date:  1987       Impact factor: 1.475

4.  Low grade pilocytic astrocytoma presenting as a spontaneous intracerebral haemorrhage in a child.

Authors:  A Golash; J Thorne; C G West
Journal:  Br J Neurosurg       Date:  1998-02       Impact factor: 1.596

5.  Fatal hemorrhage in a cerebral pilocytic astrocytoma-adult type.

Authors:  M A Lones; M A Verity
Journal:  Acta Neuropathol       Date:  1991       Impact factor: 17.088

6.  Hemorrhagic brain tumors in pediatric patients.

Authors:  J P Laurent; D A Bruce; L Schut
Journal:  Childs Brain       Date:  1981

7.  Hypothalamic juvenile pilocytic astrocytoma presenting with intracerebral hemorrhage.

Authors:  S L Hwang; T Y Huang; C Y Chai; S L Howng
Journal:  J Formos Med Assoc       Date:  1998-11       Impact factor: 3.282

Review 8.  Juvenile pilocytic astrocytoma presenting with subarachnoid hemorrhage. Case report and review of the literature.

Authors:  Ajay Garg; Manish Chugh; Shailesh B Gaikwad; Sarat P Chandra; Vipul Gupta; Nalin K Mishra; Mehar Chand Sharma
Journal:  J Neurosurg       Date:  2004-05       Impact factor: 5.115

9.  Symptomatic hemorrhage associated with recurrent pilocytic astrocytoma with granulation tissue--case report.

Authors:  Takashi Shingu; Yasuhiko Akiyama; Mitsuhiro Daisu; Nobuyuki Maruyama; Yoshifumi Matsumoto; Takeshi Miyazaki; Hidemasa Nagai; Yoshiaki Yamamoto; Toshiki Yamasaki; Manabu Yoshida; Riruke Maruyama; Kouzo Moritake
Journal:  Neurol Med Chir (Tokyo)       Date:  2007-05       Impact factor: 1.742

10.  Rate of spontaneous hemorrhage in histologically proven cases of pilocytic astrocytoma.

Authors:  J Bradley White; David G Piepgras; Bernd W Scheithauer; Joseph E Parisi
Journal:  J Neurosurg       Date:  2008-02       Impact factor: 5.115

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