Literature DB >> 27492218

Efficacy of scalp hair decontamination following exposure to vapours of sulphur mustard simulants 2-chloroethyl ethyl sulphide and methyl salicylate.

Marie Spiandore1, Anne Piram2, Alexandre Lacoste3, Philippe Prevost4, Pascal Maloni4, Franck Torre5, Laurence Asia1, Denis Josse6, Pierre Doumenq1.   

Abstract

Chemical warfare agents are an actual threat and victims' decontamination is a main concern when mass exposure occurs. Skin decontamination with current protocols has been widely documented, as well as surface decontamination. However, considering hair ability to trap chemicals in vapour phase, we investigated hair decontamination after exposure to sulphur mustard simulants methyl salicylate and 2-chloroethyl ethyl sulphide. Four decontamination protocols were tested on hair, combining showering and emergency decontamination (use of Fuller's earth or Reactive Skin Decontamination Lotion RSDL®). Both simulants were recovered from hair after treatment, but contents were significantly reduced (42-85% content allowance). Showering alone was the least efficient protocol. Concerning 2-chloroethyl ethyl sulphide, protocols did not display significant differences in decontamination efficacy. For MeS, use of emergency decontaminants significantly increased showering efficacy (10-20% rise), underlining their usefulness before thorough decontamination. Our results highlighted the need to extensively decontaminate hair after chemical exposure. Residual amounts after decontamination are challenging, as their release from hair could lead to health issues.
Copyright © 2016. Published by Elsevier B.V.

Entities:  

Keywords:  CWA; Decontamination; HD; Hair exposure; Showering

Mesh:

Substances:

Year:  2016        PMID: 27492218     DOI: 10.1016/j.cbi.2016.07.018

Source DB:  PubMed          Journal:  Chem Biol Interact        ISSN: 0009-2797            Impact factor:   5.192


  4 in total

1.  Hybrid in vitro diffusion cell for simultaneous evaluation of hair and skin decontamination: temporal distribution of chemical contaminants.

Authors:  Hazem Matar; Nevine Amer; Sneha Kansagra; Andreia Pinhal; Elliot Thomas; Scott Townend; Joanne Larner; Robert P Chilcott
Journal:  Sci Rep       Date:  2018-11-15       Impact factor: 4.379

Review 2.  Chemical warfare agent simulants for human volunteer trials of emergency decontamination: A systematic review.

Authors:  Thomas James; Stacey Wyke; Tim Marczylo; Samuel Collins; Tom Gaulton; Kerry Foxall; Richard Amlôt; Raquel Duarte-Davidson
Journal:  J Appl Toxicol       Date:  2017-10-09       Impact factor: 3.446

Review 3.  Mass Casualty Decontamination for Chemical Incidents: Research Outcomes and Future Priorities.

Authors:  Samuel Collins; Thomas James; Holly Carter; Charles Symons; Felicity Southworth; Kerry Foxall; Tim Marczylo; Richard Amlôt
Journal:  Int J Environ Res Public Health       Date:  2021-03-17       Impact factor: 3.390

4.  Human volunteer study of the decontamination of chemically contaminated hair and the consequences for systemic exposure.

Authors:  Samuel Collins; Thomas James; Felicity Southworth; Louise Davidson; Natalie Williams; Emily Orchard; Tim Marczylo; Richard Amlôt
Journal:  Sci Rep       Date:  2020-11-30       Impact factor: 4.996

  4 in total

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