| Literature DB >> 27491749 |
Jing Xu1, Shen Li1, Xiaocong Sun1, Jun Ma1, Feng Liu1, Ling Tong2, Dongho Lee3, Yasushi Ohizumi4, Muhetaer Tuerhong5, Yuanqiang Guo6.
Abstract
A phytochemical investigation of the leaves of Callicarpa kwangtungensis led to the isolation of three new diterpenoids (1-3), callipenes A-C, and eleven known analogues (4-14). Their structures were established on the basis of extensive analysis of NMR spectroscopic data, X-ray diffraction data, and experimental and calculated electronic circular dichroism spectra. Compounds 1 and 2 are rare abietane diterpenoids possessing a peroxide bridge. All of the isolates were found to inhibit LPS-induced NO production in BV-2 cells.Entities:
Keywords: 7-Oxodehydroabietic acid (PubChem CID: 620189); 7α-Hydroxydehydroabietic acid (PubChem CID: 13370054); 7β-Hydroxydehydroabietic acid (PubChem CID: 13370052); Abietane diterpenoids; Angustanoic acid F (PubChem CID: 10591519); Callicarpa kwangtungensis; Diterpenoids; NO inhibitory effects; TDDFT ECD calculations
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Year: 2016 PMID： 27491749 DOI： 10.1016/j.fitote.2016.07.012
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882