| Literature DB >> 27491357 |
Saemi O Poelma1, Seung Soo Oh2, Sameh Helmy1, Abigail S Knight2, G Leslie Burnett2, H Tom Soh3, Craig J Hawker4, Javier Read de Alaniz1.
Abstract
We present a one-photon visible light-responsive micellar system for efficient, on-demand delivery of small molecules. Release is mediated by a novel class of photochromic material - donor-acceptor Stenhouse adducts (DASAs). We demonstrate controlled delivery of small molecules such as the chemotherapeutic agent (paclitaxel) to human breast cancer cells triggered by micellar switching with low intensity, visible light.Entities:
Year: 2016 PMID: 27491357 PMCID: PMC5015652 DOI: 10.1039/c6cc04127b
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222