Tom R Karl1, Christian Stocker. 1. 1University of Queensland School of Medicine, Queensland Pediatric, Cardiac Service, Lady Cilento Children's Hospital, Brisbane, Queensland, Australia. 2Department of Cardiovascular Surgery, Johns Hopkins All Children's Hospital, St. Petersburg, Florida. 3University of Queensland, Brisbane, Queensland, Australia.
Abstract
OBJECTIVES: The objectives of this review are to discuss the anatomy, pathophysiology, surgical repair, and perioperative management strategies for tetralogy of Fallot and its variants. DATA SOURCE: MEDLINE and PubMed. CONCLUSIONS: Significant refinements have been made in the repair strategy for tetralogy of Fallot, based on improved understanding of postrepair physiology. Important considerations for timing and technique of surgery and perioperative management have been presented, and continued evolution is expected. Expanded use of the pulmonary valve reconstruction technique outlined herein, whatever the age of repair, may improve long-term outcome.
OBJECTIVES: The objectives of this review are to discuss the anatomy, pathophysiology, surgical repair, and perioperative management strategies for tetralogy of Fallot and its variants. DATA SOURCE: MEDLINE and PubMed. CONCLUSIONS: Significant refinements have been made in the repair strategy for tetralogy of Fallot, based on improved understanding of postrepair physiology. Important considerations for timing and technique of surgery and perioperative management have been presented, and continued evolution is expected. Expanded use of the pulmonary valve reconstruction technique outlined herein, whatever the age of repair, may improve long-term outcome.
Authors: Yan Zhao; Xuedong Kang; Fuying Gao; Alejandra Guzman; Ryan P Lau; Reshma Biniwale; Madhuri Wadehra; Brian Reemtsen; Meena Garg; Nancy Halnon; Fabiola Quintero-Rivera; Glen Van Arsdell; Giovanni Coppola; Stanley F Nelson; Marlin Touma Journal: J Mol Med (Berl) Date: 2019-12-13 Impact factor: 4.599
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