Literature DB >> 27489528

Current and Emerging Treatments for Alpha-1 Antitrypsin Deficiency.

David H Perlmutter1.   

Abstract

Entities:  

Year:  2016        PMID： 27489528      PMCID： PMC4969782     

Source DB:  PubMed          Journal:  Gastroenterol Hepatol (N Y)        ISSN： 1554-7914


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  9 in total

1.  Two New Considerations for Improving the Diagnosis of α1-Antitrypsin Deficiency-Associated Liver Disease.

Authors:  David H Perlmutter; Kapil Chopra; Andrew Chu
Journal:  Dig Dis Sci       Date:  2015-06       Impact factor: 3.199

2.  An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis.

Authors:  Tunda Hidvegi; Michael Ewing; Pamela Hale; Christine Dippold; Caroline Beckett; Carolyn Kemp; Nicholas Maurice; Amitava Mukherjee; Christina Goldbach; Simon Watkins; George Michalopoulos; David H Perlmutter
Journal:  Science       Date:  2010-06-03       Impact factor: 47.728

3.  Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice.

Authors:  Shuling Guo; Sheri L Booten; Mariam Aghajan; Gene Hung; Chenguang Zhao; Keith Blomenkamp; Danielle Gattis; Andrew Watt; Susan M Freier; Jeffery H Teckman; Michael L McCaleb; Brett P Monia
Journal:  J Clin Invest       Date:  2013-12-20       Impact factor: 14.808

4.  Alpha-1-antitrypsin deficiency: outcomes after liver transplantation.

Authors:  N Kemmer; T Kaiser; V Zacharias; G W Neff
Journal:  Transplant Proc       Date:  2008-06       Impact factor: 1.066

5.  Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency.

Authors:  S Eriksson; J Carlson; R Velez
Journal:  N Engl J Med       Date:  1986-03-20       Impact factor: 91.245

6.  Liver carcinoma in PiZ alpha-1-antitrypsin deficiency.

Authors:  H Zhou; H P Fischer
Journal:  Am J Surg Pathol       Date:  1998-06       Impact factor: 6.394

7.  Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells.

Authors:  Kosuke Yusa; S Tamir Rashid; Helene Strick-Marchand; Ignacio Varela; Pei-Qi Liu; David E Paschon; Elena Miranda; Adriana Ordóñez; Nicholas R F Hannan; Foad J Rouhani; Sylvie Darche; Graeme Alexander; Stefan J Marciniak; Noemi Fusaki; Mamoru Hasegawa; Michael C Holmes; James P Di Santo; David A Lomas; Allan Bradley; Ludovic Vallier
Journal:  Nature       Date:  2011-10-12       Impact factor: 49.962

Review 8.  Mysteries of α1-antitrypsin deficiency: emerging therapeutic strategies for a challenging disease.

Authors:  Raafe Ghouse; Andrew Chu; Yan Wang; David H Perlmutter
Journal:  Dis Model Mech       Date:  2014-04       Impact factor: 5.758

Review 9.  Capitalizing on the autophagic response for treatment of liver disease caused by alpha-1-antitrypsin deficiency and other genetic diseases.

Authors:  Andrew S Chu; David H Perlmutter; Yan Wang
Journal:  Biomed Res Int       Date:  2014-06-03       Impact factor: 3.411
  9 in total
  2 in total

Review 1.  Alpha-1 Antitrypsin Deficiency-Mediated Liver Toxicity: Why Do Some Patients Do Poorly? What Do We Know So Far?

Authors:  Marion Bouchecareilh
Journal:  Chronic Obstr Pulm Dis       Date:  2020-07

Review 2.  Alpha-1 antitrypsin deficiency: outstanding questions and future directions.

Authors:  María Torres-Durán; José Luis Lopez-Campos; Miriam Barrecheguren; Marc Miravitlles; Beatriz Martinez-Delgado; Silvia Castillo; Amparo Escribano; Adolfo Baloira; María Mercedes Navarro-Garcia; Daniel Pellicer; Lucía Bañuls; María Magallón; Francisco Casas; Francisco Dasí
Journal:  Orphanet J Rare Dis       Date:  2018-07-11       Impact factor: 4.123
  2 in total

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