Literature DB >> 27487819

Heel ulcers do heal in patients with diabetes.

Hedvig Örneholm1, Jan Apelqvist2, Jan Larsson1, Magnus Eneroth1.   

Abstract

A heel ulcer is considered to be a serious complication in patients with diabetes, and there is limited information regarding outcome. In most of the literature, a poor prognosis is described. The aim of this study was to investigate a large cohort of ulcers located in the heel in patients with diabetes. Seven hundred and sixty-eight patients [median age 73 (17-98)], presenting with a heel ulcer at a multidisciplinary diabetes foot clinic, fulfilled the inclusion criteria and were followed-up until final outcome. Fifty-eight per cent of the patients healed primarily; 7% healed after major debridement; 9% healed after amputation and 25% died unhealed. Median healing time was 17 weeks. Ulcer progression was seen in 19% of patients. Thirty-one percent of patients had severe peripheral vascular disease. A creatinine level below 91 µmol/l was related to a higher probability for healing without major debridement or amputation, whereas vascular surgery, nephropathy and oedema were related to a lower probability for healing without major debridement or amputation. Two thirds of heel ulcers do heal in patients with diabetes despite patients being elderly and with extensive comorbidity. The extent of peripheral vascular disease, nephropathy, oedema and decreased renal function are important factors influencing outcome.
© 2016 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

Entities:  

Keywords:  Diabetes; Healing; Heel ulcer; Outcome

Mesh:

Year:  2016        PMID: 27487819      PMCID: PMC7950186          DOI: 10.1111/iwj.12654

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  24 in total

1.  Diabetic heel ulcer in the Sudan: determinants of outcome.

Authors:  Haseeb E Bakheit; Mohamed F Mohamed; Seif ElDin I Mahadi; Abu Bakr H Widatalla; Mohamed A Shawer; Amar H Khamis; Mohamed E Ahmed
Journal:  J Foot Ankle Surg       Date:  2011-11-10       Impact factor: 1.286

2.  The dysvascular foot: a system for diagnosis and treatment.

Authors:  F W Wagner
Journal:  Foot Ankle       Date:  1981-09

3.  Subtotal calcanectomy for the treatment of large heel ulceration and calcaneal osteomyelitis in the diabetic patient.

Authors:  B Baravarian; M M Menendez; D J Weinheimer; C Lowery; R Kosanovich; L Vidt
Journal:  J Foot Ankle Surg       Date:  1999 May-Jun       Impact factor: 1.286

4.  Prognostic value of systolic ankle and toe blood pressure levels in outcome of diabetic foot ulcer.

Authors:  J Apelqvist; J Castenfors; J Larsson; A Stenström; C D Agardh
Journal:  Diabetes Care       Date:  1989-06       Impact factor: 19.112

5.  The effects of ulcer size and site, patient's age, sex and type and duration of diabetes on the outcome of diabetic foot ulcers.

Authors:  S O Oyibo; E B Jude; I Tarawneh; H C Nguyen; D G Armstrong; L B Harkless; A J Boulton
Journal:  Diabet Med       Date:  2001-02       Impact factor: 4.359

6.  High probability of healing without amputation of plantar forefoot ulcers in patients with diabetes.

Authors:  Hedvig Örneholm; Jan Apelqvist; Jan Larsson; Magnus Eneroth
Journal:  Wound Repair Regen       Date:  2015-10-19       Impact factor: 3.617

7.  Heel ulcers don't heal in diabetes. Or do they?

Authors:  S Y Chipchase; K A Treece; N Pound; F L Game; W J Jeffcoate
Journal:  Diabet Med       Date:  2005-09       Impact factor: 4.359

Review 8.  Options for diabetic patients with chronic heel ulcers.

Authors:  J J Cevera; L L Bolton; M D Kerstein
Journal:  J Diabetes Complications       Date:  1997 Nov-Dec       Impact factor: 2.852

9.  Diabetic foot disease: impact of ulcer location on ulcer healing.

Authors:  Kristy M Pickwell; Volkert D Siersma; Marleen Kars; Per E Holstein; Nicolaas C Schaper
Journal:  Diabetes Metab Res Rev       Date:  2013-07       Impact factor: 4.876

Review 10.  Diabetic heel ulcers: a major risk factor for lower extremity amputation.

Authors:  Nidal A Younes; Abla M Albsoul; Hamzeh Awad
Journal:  Ostomy Wound Manage       Date:  2004-06       Impact factor: 2.629

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Journal:  Adv Wound Care (New Rochelle)       Date:  2019-05-03       Impact factor: 4.730

2.  Proteomic Analysis of Peri-Wounding Tissue Expressions in Extracorporeal Shock Wave Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model.

Authors:  Rong-Fu Chen; Ming-Yu Yang; Ching-Jen Wang; Chun-Ting Wang; Yur-Ren Kuo
Journal:  Int J Mol Sci       Date:  2020-07-30       Impact factor: 5.923

3.  Heal or no heel: Outcomes of ischaemic heel ulcers following lower limb revascularization from a multi-ethnic Asian Cohort in Singapore.

Authors:  Yun Le Linn; Sze Ling Chan; Shereen Xue Yun Soon; Charyl Jia Qi Yap; Mervin Nathan Han Hui Lim; Qing Wei Shaun Lee; Tze Tec Chong; Tjun Yip Tang
Journal:  Int Wound J       Date:  2020-08-24       Impact factor: 3.315

  3 in total

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