Camilla B Pimentel1, Jerry H Gurwitz2, Jennifer Tjia1, Anne L Hume3,4, Kate L Lapane5. 1. Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts. 2. Meyers Primary Care Institute, Worcester, Massachusetts. 3. Department of Family Medicine, Alpert Medical School, Brown University, Memorial Hospital of Rhode Island, Providence, Rhode Island. 4. Department of Pharmacy Practice, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island. 5. Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts. kate.lapane@umassmed.edu.
Abstract
OBJECTIVES: To estimate the prevalence of new initiation of long-acting opioids since introduction of national efforts to increase prescriber and public awareness on safe use of transdermal fentanyl patches. DESIGN: Cross-sectional. SETTING: U.S. nursing homes (NHs). PARTICIPANTS: Medicare-enrolled long-stay NH residents (N = 22,253). MEASUREMENTS: Minimum Data Set 3.0 was linked with Medicare enrollment, hospital claims, and prescription drug transaction data (January-December 2011) and used to determine the prevalence of new initiation of a long-acting opioid prescribed to residents in NHs. RESULTS: Of NH residents prescribed a long-acting opioid within 30 days of NH admission (n = 12,278), 9.4% (95% confidence interval = 8.9-9.9%) lacked a prescription drug claim for a short-acting opioid in the previous 60 days. The most common initial prescriptions of long-acting opioids were fentanyl patch (51.9% of opioid-naïve NH residents), morphine sulfate (28.1%), and oxycodone (17.2%). CONCLUSION: New initiation of long-acting opioids-especially fentanyl patches, which have been the subject of safety communications-persists in NHs.
OBJECTIVES: To estimate the prevalence of new initiation of long-acting opioids since introduction of national efforts to increase prescriber and public awareness on safe use of transdermal fentanyl patches. DESIGN: Cross-sectional. SETTING: U.S. nursing homes (NHs). PARTICIPANTS: Medicare-enrolled long-stay NH residents (N = 22,253). MEASUREMENTS: Minimum Data Set 3.0 was linked with Medicare enrollment, hospital claims, and prescription drug transaction data (January-December 2011) and used to determine the prevalence of new initiation of a long-acting opioid prescribed to residents in NHs. RESULTS: Of NH residents prescribed a long-acting opioid within 30 days of NH admission (n = 12,278), 9.4% (95% confidence interval = 8.9-9.9%) lacked a prescription drug claim for a short-acting opioid in the previous 60 days. The most common initial prescriptions of long-acting opioids were fentanyl patch (51.9% of opioid-naïve NH residents), morphine sulfate (28.1%), and oxycodone (17.2%). CONCLUSION: New initiation of long-acting opioids-especially fentanyl patches, which have been the subject of safety communications-persists in NHs.
Authors: Sherrie E Aspinall; Xinhua Zhao; Chester B Good; Roslyn A Stone; Kenneth J Smith; Francesca E Cunningham Journal: Am J Manag Care Date: 2013-09 Impact factor: 2.229
Authors: Andrew D Wiese; Marie R Griffin; William Schaffner; C Michael Stein; Robert A Greevy; Edward F Mitchel; Carlos G Grijalva Journal: Clin Infect Dis Date: 2019-05-17 Impact factor: 9.079
Authors: Jacob N Hunnicutt; Stavroula A Chrysanthopoulou; Christine M Ulbricht; Anne L Hume; Jennifer Tjia; Kate L Lapane Journal: J Am Geriatr Soc Date: 2017-09-21 Impact factor: 5.562
Authors: Jacob N Hunnicutt; Anne L Hume; Christine M Ulbricht; Jennifer Tjia; Kate L Lapane Journal: Pharmacoepidemiol Drug Saf Date: 2018-06-04 Impact factor: 2.890
Authors: Kevin M Fain; Carlos Castillo-Salgado; David D Dore; Jodi B Segal; Andrew R Zullo; G Caleb Alexander Journal: J Am Med Dir Assoc Date: 2016-10-06 Impact factor: 4.669