Literature DB >> 27485836

Laboratory Innovation Towards Quality Program Sustainability.

Alash'le Abimiku1, Ralph Timperi2, William Blattner3,4.   

Abstract

Laboratory innovation significantly affects program sustainability of HIV programs in low and middle income countries (LMICs) far beyond its immediate sphere of impact. Innovation in rapid development of diagnostic technologies, improved quality management systems, strengthened laboratory management, affordable external quality assurance and accreditation schemes, and building local capacity have reduced costs, brought quality improvement to point-of-care testing, increased access to testing services, reduced treatment and prevention costs and opened the door to the real possibility of ending the AIDS epidemic. However, for effectively implemented laboratory innovation to contribute to HIV quality program sustainability, it must be implemented within the overall context of the national strategic plan and HIV treatment programs. The high quality of HIV rapid diagnostic test was a breakthrough that made it possible for more persons to learn their HIV status, receive counseling, and if infected to receive treatment. Likewise, the use of dried blood spots made the shipment of samples easier for the assessment of different variables of HIV infection-molecular diagnosis, CD4+ cell counts, HIV antibodies, drug resistance surveillance, and even antiretroviral drug level measurements. Such advancement is critical for to reaching the UNAIDS target of 90-90-90 and for bringing the AIDS epidemic to an end, especially in LMICs.

Entities:  

Keywords:  Diagnosis; HIV; Innovation; Laboratory; Point-of-care; Quality

Mesh:

Year:  2016        PMID: 27485836     DOI: 10.1007/s11904-016-0323-y

Source DB:  PubMed          Journal:  Curr HIV/AIDS Rep        ISSN: 1548-3568            Impact factor:   5.071


  22 in total

1.  Rapid testing strategies for HIV-1 serodiagnosis in high-prevalence African settings.

Authors:  Richard J Wright; Jeffrey S A Stringer
Journal:  Am J Prev Med       Date:  2004-07       Impact factor: 5.043

2.  A RealTime HIV-1 viral load assay for automated quantitation of HIV-1 RNA in genetically diverse group M subtypes A-H, group O and group N samples.

Authors:  Ning Tang; Shihai Huang; John Salituro; Wai-Bing Mak; Gavin Cloherty; Julie Johanson; Yu Hong Li; George Schneider; John Robinson; John Hackett; Priscilla Swanson; Klara Abravaya
Journal:  J Virol Methods       Date:  2007-08-17       Impact factor: 2.014

3.  The WHO/PEPFAR collaboration to prepare an operations manual for HIV prevention, care, and treatment at primary health centers in high-prevalence, resource-constrained settings: defining laboratory services.

Authors:  Thomas Spira; Mary Lou Lindegren; Robert Ferris; Vincent Habiyambere; Tedd Ellerbrock
Journal:  Am J Clin Pathol       Date:  2009-06       Impact factor: 2.493

4.  Scaling up HIV rapid testing in developing countries: comprehensive approach for implementing quality assurance.

Authors:  Bharat S Parekh; Mireille B Kalou; George Alemnji; Chin-Yih Ou; Guy-Michel Gershy-Damet; John N Nkengasong
Journal:  Am J Clin Pathol       Date:  2010-10       Impact factor: 2.493

Review 5.  HIV testing in developing countries: what is required?

Authors:  George Alemnji; John N Nkengasong; Bharat S Parekh
Journal:  Indian J Med Res       Date:  2011-12       Impact factor: 2.375

Review 6.  Tracking the progress of HIV: the impact of point-of-care tests on antiretroviral therapy.

Authors:  Steven D Reid; Sarah J Fidler; Graham S Cooke
Journal:  Clin Epidemiol       Date:  2013-09-26       Impact factor: 4.790

7.  Inaccurate diagnosis of HIV-1 group M and O is a key challenge for ongoing universal access to antiretroviral treatment and HIV prevention in Cameroon.

Authors:  Avelin F Aghokeng; Eitel Mpoudi-Ngole; Henriette Dimodi; Arrah Atem-Tambe; Marcel Tongo; Christelle Butel; Eric Delaporte; Martine Peeters
Journal:  PLoS One       Date:  2009-11-06       Impact factor: 3.240

Review 8.  HIV testing and care in Burkina Faso, Kenya, Malawi and Uganda: ethics on the ground.

Authors:  Carla Makhlouf Obermeyer; Sarah Bott; Ron Bayer; Alice Desclaux; Rachel Baggaley
Journal:  BMC Int Health Hum Rights       Date:  2013-01-23

9.  The evaluation of a rapid in situ HIV confirmation test in a programme with a high failure rate of the WHO HIV two-test diagnostic algorithm.

Authors:  Derryck B Klarkowski; Joseph M Wazome; Kamalini M Lokuge; Leslie Shanks; Clair F Mills; Daniel P O'Brien
Journal:  PLoS One       Date:  2009-02-06       Impact factor: 3.240

10.  Rapid Tests versus ELISA for Screening of HIV Infection: Our Experience from a Voluntary Counselling and Testing Facility of a Tertiary Care Centre in North India.

Authors:  Bhanu Mehra; Sonali Bhattar; Preena Bhalla; Deepti Rawat
Journal:  ISRN AIDS       Date:  2014-04-07
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  1 in total

1.  Baseline assessment findings of the Africa Society for Blood Transfusion Step-Wise Accreditation Programme in 10 sub-Saharan African countries, 2016-2018.

Authors:  Udhayashankar Kanagasabai; Michael Qualls; Ray W Shiraishi; Laura Eno; Innocent Zungu; Lesley Bust; Bakary Drammeh; Dejana Selenic
Journal:  Vox Sang       Date:  2022-03-10       Impact factor: 2.996

  1 in total

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