Brian G Harbrecht1, Nick A Nash1. 1. The Hiram C. Polk, Jr. MD Department of Surgery and the Price Institute for Surgical Research, University of Louisville , Louisville, Kentucky.
Abstract
BACKGROUND: Soft tissue infections are a common reason for general surgical consultation. Necrotizing soft tissue infections (NSTI) are a rapidly progressive form of this infection that account for significant morbidity and many deaths. METHODS: Review of relevant English-language publications. RESULTS: There are approximately 500-1,500 cases of NSTI annually in the United States, although accurate estimates of their frequency are difficult to obtain. These infections may be polymicrobial or monomicrobial, and substantial regional heterogeneity exists regarding anatomic location and the involved organisms. Source control with early surgical debridement and targeted anti-microbial therapy are the mainstays of treatment. CONCLUSION: Necrotizing soft tissue infections remain a common indication for general surgical consultation. Early diagnosis and prompt surgical treatment are essential for effective control.
BACKGROUND: Soft tissue infections are a common reason for general surgical consultation. Necrotizing soft tissue infections (NSTI) are a rapidly progressive form of this infection that account for significant morbidity and many deaths. METHODS: Review of relevant English-language publications. RESULTS: There are approximately 500-1,500 cases of NSTI annually in the United States, although accurate estimates of their frequency are difficult to obtain. These infections may be polymicrobial or monomicrobial, and substantial regional heterogeneity exists regarding anatomic location and the involved organisms. Source control with early surgical debridement and targeted anti-microbial therapy are the mainstays of treatment. CONCLUSION:Necrotizing soft tissue infections remain a common indication for general surgical consultation. Early diagnosis and prompt surgical treatment are essential for effective control.
Authors: Dara L Horn; Emma A Roberts; Jolie Shen; Jeannie D Chan; Eileen M Bulger; Noel S Weiss; John B Lynch; Chloe Bryson-Cahn; Bryce R H Robinson Journal: Clin Infect Dis Date: 2021-12-06 Impact factor: 9.079
Authors: Dara L Horn; Jolie Shen; Emma Roberts; Theresa N Wang; Kevin S Li; Grant E O'Keefe; Joseph Cuschieri; Eileen M Bulger; Bryce R H Robinson Journal: J Trauma Acute Care Surg Date: 2020-07 Impact factor: 3.697