Literature DB >> 27482641

MYOPIC CHOROIDAL NEOVASCULARIZATION: Diagnosis and Treatment.

Timothy Y Y Lai1, Chui Ming Gemmy Cheung.   

Abstract

PURPOSE: To review and summarize the latest developments in the diagnosis and management of myopic choroidal neovascularization (mCNV).
METHODS: A review of the literature was performed, focusing on tests and investigations for diagnosing mCNV, as well as the key treatment options available for mCNV.
RESULTS: Standard essential tests and investigations for diagnosing mCNV include spectral-domain optical coherence tomography for screening, fluorescein angiography for confirmation, and indocyanine green angiography and fundus autofluorescence for providing supplementary information. The current first line treatment of mCNV is the use of anti-vascular endothelial growth factor therapy.
CONCLUSION: Various investigations can assist the differentiation of mCNV from other coexisting retinal pathologies associated with myopia or choroidal neovascularization resulting from other causes. Prompt use of anti-vascular endothelial growth factor therapy has good efficacy and safety in the treatment of mCNV.

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Year:  2016        PMID: 27482641     DOI: 10.1097/IAE.0000000000001227

Source DB:  PubMed          Journal:  Retina        ISSN: 0275-004X            Impact factor:   4.256


  7 in total

1.  Retinal pigmental epithelium elevation and external limiting membrane interruption in myopic choroidal neovascularization: correlation with activity.

Authors:  Xiaoyan Ding; Zongyi Zhan; Limei Sun; Yu Yang; Songshan Li; Aiyuan Zhang; Xiaoling Luo; Lin Lu
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2018-07-07       Impact factor: 3.117

2.  Regional analysis of segmented-macular structure in patients with myopic anisometropia.

Authors:  Furkan Kirik; Cansu Ekinci; Ersin Akbulut; Havvanur Bayraktar; Hakan Ozdemir
Journal:  Int Ophthalmol       Date:  2021-06-29       Impact factor: 2.031

3.  Long-term outcomes of the intravitreal injection of ranibizumab for the treatment of choroidal neovascularization secondary to pathologic myopia.

Authors:  Ewa Wasiluk; Malgorzata Wojnar; Iwona Obuchowska; Zofia Mariak
Journal:  Int Ophthalmol       Date:  2019-12-02       Impact factor: 2.031

4.  Puerarin suppresses hypoxia-induced vascular endothelial growth factor upregulation in human retinal pigmented epithelial cells by blocking JAK2/STAT3 pathway.

Authors:  Huixin Tang; Lingchun Kong; Yuqin Yang; Jingjing Li; Hong Zou
Journal:  Bioengineered       Date:  2022-05       Impact factor: 6.832

5.  EFFICACY AND SAFETY OF RANIBIZUMAB FOR THE TREATMENT OF CHOROIDAL NEOVASCULARIZATION DUE TO UNCOMMON CAUSE: Twelve-Month Results of the MINERVA Study.

Authors:  Timothy Y Y Lai; Giovanni Staurenghi; Paolo Lanzetta; Frank G Holz; Shiao Hui Melissa Liew; Sabine Desset-Brethes; Harry Staines; Philip G Hykin
Journal:  Retina       Date:  2018-08       Impact factor: 4.256

6.  Association between choriocapillaris flow deficit and choroidal neovascularization activity in eyes with myopic choroidal neovascularization.

Authors:  Sato Uematsu; Hirokazu Sakaguchi; Kaori Sayanagi; Yasushi Ikuno; Ayako Yokoyama; Tomoko Asai; Yoko Fukushima; Chikako Hara; Susumu Sakimoto; Kohji Nishida
Journal:  Sci Rep       Date:  2021-11-09       Impact factor: 4.379

7.  Real-world effectiveness and safety of ranibizumab for the treatment of myopic choroidal neovascularization: Results from the LUMINOUS study.

Authors:  Robin D Hamilton; Andreas Clemens; Angelo Maria Minnella; Timothy Y Y Lai; Hong Dai; Taiji Sakamoto; Chui Ming Gemmy Cheung; Nor Fariza Ngah; Cornelia Dunger-Baldauf; Frank G Holz
Journal:  PLoS One       Date:  2020-01-21       Impact factor: 3.240

  7 in total

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