| Literature DB >> 27479881 |
Christopher B Rodell1, Neville N Dusaj1, Christopher B Highley1, Jason A Burdick2.
Abstract
Double-network theory is extended to include guest-host interactions, enabling injectability and cytcompatibility of tough hydrogels. Noncovalent interactions are used as a sacrificial network to toughen covalently crosslinked hydrogels formed from hyaluronic acid. Shear thinning of supramolecular bonds allows hydrogel injection and rapid self-healing, while gentle reaction conditions permit cell encapsulation with high viability.Entities:
Keywords: biomaterials; double networks; supramolecular chemistry; tissue engineering
Year: 2016 PMID: 27479881 DOI: 10.1002/adma.201602268
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849