Eduardo Scortegagna1, Adib R Karam2, Shirin Sioshansi3, Adel Bozorgzadeh4, Curtis Barry5, Sarwat Hussain2. 1. Radiology Department, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655. Electronic address: scortegagnajunior@gmail.com. 2. Radiology Department, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655. 3. Radiation Oncology Department, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655. 4. Department of Surgery, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655. 5. Department of Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655.
Abstract
PURPOSE: This study aims to evaluate the recurrence pattern of hepatocellular carcinoma (HCC) following liver transplantation. MATERIALS AND METHODS: A total of 54 patients underwent liver transplantation for HCC; 9 patients developed biopsy-proven recurrent HCC (16.6%). The site of HCC recurrence along with other factors was analyzed. RESULTS: Seven patients were diagnosed with HCC prior to liver transplantation and 2 patients had incidental HCC in the explanted liver. Two patients had locoregional recurrence, 4 patients had distant metastasis, and 3 patients had synchronous locoregional recurrence and distant metastasis. CONCLUSION: A significant proportion of HCC recurrence following liver transplantation is extrahepatic.
PURPOSE: This study aims to evaluate the recurrence pattern of hepatocellular carcinoma (HCC) following liver transplantation. MATERIALS AND METHODS: A total of 54 patients underwent liver transplantation for HCC; 9 patients developed biopsy-proven recurrent HCC (16.6%). The site of HCC recurrence along with other factors was analyzed. RESULTS: Seven patients were diagnosed with HCC prior to liver transplantation and 2 patients had incidental HCC in the explanted liver. Two patients had locoregional recurrence, 4 patients had distant metastasis, and 3 patients had synchronous locoregional recurrence and distant metastasis. CONCLUSION: A significant proportion of HCC recurrence following liver transplantation is extrahepatic.
Authors: Mohamed Abdel Wahab; Ahmed Shehta; Eman M Ibrahim; Rehab T Eldesoky; Ahmed A Sultan; Khaled R Zalata; Omar Fathy; Mohamed Elshoubary; Tarek Salah; Amr M Yassen; Mohamed Elmorshedi; Ahmed Monier; Ahmed Farouk; Usama Shiha Journal: Int J Surg Case Rep Date: 2018-11-27