Morris J Brown1, William M Drake2. 1. Barts Heart Centre, William Harvey Research Institute, Queen Mary University London, London WCIM 6BQ, UK; Barts and the London Medical School, London, UK. Electronic address: morris.brown@qmul.ac.uk. 2. Barts Heart Centre, William Harvey Research Institute, Queen Mary University London, London WCIM 6BQ, UK; Barts and the London Medical School, London, UK.