| Literature DB >> 27473941 |
Anna Martha Vaitses Fontanari1, Angelo Brandelli Costa2, Bianca Aguiar3, Cíntia Tusset4, Tahiana Andreazza5, Maiko Schneider6, Eduarda Dias da Rosa7, Bianca Machado Borba Soll8, Karine Schwarz9, Dhiordan Cardoso da Silva10, André Oliveira Borba11, Andressa Mueller12, Raffael Massuda13, Maria Inês Rodrigues Lobato14.
Abstract
Serum BDNF levels are significantly decreased in transsexual Brazilian women when compared to cis-sexual men. Since transsexual men are also exposed to chronic social stress and have a high prevalence of associated psychopathologies, it is plausible to inquire if BDNF serum levels are altered in transsexual men as well. Therefore, our objective was to evaluate differences in BDNF serum level of transsexual men when compared to cis-sexual men and women. Our sample comprises 27 transsexual men, 31 cis-sexual women and 30 cis-sexual men recruited between 2011 and 2015. We observed that BDNF serum concentration is decreased in transsexual men comparing to cis-sexual men and women. Cross-sex hormone treatment, chronic social stress or long-term gender dysphoria (GD) could explain the variation found in BDNF serum levels.Entities:
Keywords: BDNF; Gender dysphoria; Neurotrophin; Transgender; Transsexualism; Transsexuality
Mesh：
Substances：
Year: 2016 PMID： 27473941 DOI： 10.1016/j.neulet.2016.07.034
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046