Literature DB >> 27472888

Choosing an Advanced Therapy in Parkinson's Disease; is it an Evidence-Based Decision in Current Practice?

Frouke A P Nijhuis1,2, Jolien van Heek3, Bastiaan R Bloem3, Bart Post3, Marjan J Faber4.   

Abstract

BACKGROUND: In advanced Parkinson's disease (PD), neurologists and patients face a complex decision for an advanced therapy. When choosing a treatment, the best available evidence should be combined with the professional's expertise and the patient's preferences.
OBJECTIVE: The objective of this study was to explore current decision-making in advanced PD.
METHODS: We conducted focus group discussions and individual interviews with patients (N = 20) who had received deep brain stimulation, Levodopa-Carbidopa intestinal gel, or subcutaneous apomorphine infusion, and with their caregivers (N = 16). Furthermore, we conducted semi-structured interviews with neurologists (N = 7) and PD nurse specialists (N = 3) to include the perspectives of all key players in this decision-making process. Data were analyzed by two researchers using a qualitative thematic analysis approach.
RESULTS: Four themes representing current experiences with the decision-making process were identified: 1) information and information needs, 2) factors influencing treatment choice and individual decision strategies, 3) decision-making roles, and 4) barriers and facilitators to shared decision-making (SDM). Patient preferences were taken into account, however patients were not always provided with adequate information. The professional's expertise influenced the decision-making process in both positive and negative ways. Although professionals and patients considered SDM essential for the decision of an advanced treatment, they mentioned several barriers for the implementation in current practice.
CONCLUSIONS: In this study we found several factors explaining why in current practice, evidence-based decision-making in advanced PD is not optimal. An important first step would be to develop objective information on all treatment options.

Entities:  

Keywords:  Parkinson’s disease; evidence-based medicine; qualitative research; shared decision-making

Mesh:

Substances:

Year:  2016        PMID: 27472888     DOI: 10.3233/JPD-160816

Source DB:  PubMed          Journal:  J Parkinsons Dis        ISSN: 1877-7171            Impact factor:   5.568


  7 in total

1.  Complex therapies for advanced Parkinson's disease: what is the role of doctor-patient communication?

Authors:  Elisa Montanaro; Carlo Alberto Artusi; Maurizio Zibetti; Leonardo Lopiano
Journal:  Neurol Sci       Date:  2019-06-28       Impact factor: 3.307

Review 2.  Intrajejunal Infusion of Levodopa/Carbidopa for Advanced Parkinson's Disease: A Systematic Review.

Authors:  Taiji Tsunemi; Genko Oyama; Shinji Saiki; Taku Hatano; Jiro Fukae; Yasushi Shimo; Nobutaka Hattori
Journal:  Mov Disord       Date:  2021-04-25       Impact factor: 9.698

3.  Are Patients Ready for "EARLYSTIM"? Attitudes towards Deep Brain Stimulation among Female and Male Patients with Moderately Advanced Parkinson's Disease.

Authors:  Maria Sperens; Katarina Hamberg; Gun-Marie Hariz
Journal:  Parkinsons Dis       Date:  2017-03-28

4.  Barriers and facilitators of communication about off periods in Parkinson's disease: Qualitative analysis of patient, carepartner, and physician Interviews.

Authors:  Melissa J Armstrong; Tara Rastgardani; Anna R Gagliardi; Connie Marras
Journal:  PLoS One       Date:  2019-04-18       Impact factor: 3.240

5.  Communication About OFF Periods in Parkinson's Disease: A Survey of Physicians, Patients, and Carepartners.

Authors:  Tara Rastgardani; Melissa J Armstrong; Anna R Gagliardi; Arthur Grabovsky; Connie Marras
Journal:  Front Neurol       Date:  2019-08-19       Impact factor: 4.003

6.  Access and Use of Device-Aided Therapies for Parkinson's Disease in Denmark.

Authors:  Tove Henriksen; Kim Peder Dalhoff; Henriette Engel Hansen; Andreas W Brenneche; Ulla Sofie Lønberg; Erik Hvid Danielsen
Journal:  Mov Disord Clin Pract       Date:  2020-07-02

7.  Cost-Effectiveness of Device-Aided Therapies in Parkinson's Disease: A Structured Review.

Authors:  Katarzyna Smilowska; Daniel J van Wamelen; Tomasz Pietrzykowski; Alexander Calvano; Carmen Rodriguez-Blazquez; Pablo Martinez-Martin; Per Odin; K Ray Chaudhuri
Journal:  J Parkinsons Dis       Date:  2021       Impact factor: 5.568

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.