Literature DB >> 27470105

Detection and Analysis of Ebola Virus in Sierra Leone-China Friendship Biosafety Laboratory from March 11 to April 20, 2015.

Qin Wang1, Yong Zhang1, Huan Yu Wang2, Hai Jun DU2, Kai Nie3, Jing Dong Song2, Kang Xiao4, Wen Wen Lei2, Jian Qiang Guo3, He Jiang Wei3, Kun Cai3, Yan Hai Wang3, Jiang Wu3, Gerald Bangura5, Idrissa Laybohr Kamara5, Xiao Ping Dong6.   

Abstract

Ebola virus disease reemerged in Western Africa in 2014. Chinese Center for Disease Control and Prevention dispatched the first Ebola virus (EBOV) detection team to run newly established Sierra Leone-China Friendship Biological Safety Laboratory. The aims of study were to understand epidemiology, clinical manifestations and survival time of EBOV in patient's blood. A total of 913 specimens were tested between March 11 and April 20, 2015. EBOV positivity occurred in 7.37% of the blood and 0.53% in throat swabs. Most commonly reported symptoms of laboratory confirmed patients were intense fatigue, anorexia, and fever. EBOV RNAs persisted in blood for almost 4 weeks and the real-time RT-PCR Ct values showed close correlation with the sampling time after onset.
Copyright © 2016 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.

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Year:  2016        PMID: 27470105     DOI: 10.3967/bes2016.057

Source DB:  PubMed          Journal:  Biomed Environ Sci        ISSN: 0895-3988            Impact factor:   3.118


  4 in total

1.  Ebola RNA Persistence in Semen of Ebola Virus Disease Survivors - Final Report.

Authors:  Gibrilla F Deen; Nathalie Broutet; Wenbo Xu; Barbara Knust; Foday R Sesay; Suzanna L R McDonald; Elizabeth Ervin; Jaclyn E Marrinan; Philippe Gaillard; Ndema Habib; Hongtu Liu; William Liu; Anna E Thorson; Francis Yamba; Thomas A Massaquoi; Faustin James; Archchun Ariyarajah; Christine Ross; Kyle Bernstein; Antoine Coursier; John Klena; Marylin Carino; Alie H Wurie; Yong Zhang; Marion S Dumbuya; Neetu Abad; Baimba Idriss; Teodora Wi; Sarah D Bennett; Tina Davies; Faiqa K Ebrahim; Elissa Meites; Dhamari Naidoo; Samuel J Smith; Patricia Ongpin; Tasneem Malik; Anshu Banerjee; Bobbie R Erickson; Yongjian Liu; Yang Liu; Ke Xu; Aaron Brault; Kara N Durski; Jörn Winter; Tara Sealy; Stuart T Nichol; Margaret Lamunu; James Bangura; Sihem Landoulsi; Amara Jambai; Oliver Morgan; Guizhen Wu; Mifang Liang; Qiudong Su; Yu Lan; Yanzhe Hao; Pierre Formenty; Ute Ströher; Foday Sahr
Journal:  N Engl J Med       Date:  2015-10-14       Impact factor: 91.245

2.  Comprehensive Clinical and Laboratory Follow-up of a Female Patient With Ebola Virus Disease: Sierra Leone Ebola Virus Persistence Study.

Authors:  William J Liu; Foday R Sesay; Antoine Coursier; Barbara Knust; Jaclyn E Marrinan; Shannon Whitmer; Suzanna L R McDonald; Philippe Gaillard; Yang Liu; Qiudong Su; Yong Zhang; Ian Crozier; Archchun Ariyarajah; Marylin Carino; Thomas Massaquoi; Nathalie Broutet; Wenbo Xu; Guizhen Wu; Ute Ströher; George F Gao; Pierre Formenty; Foday Sahr; Gibrilla F Deen
Journal:  Open Forum Infect Dis       Date:  2019-02-26       Impact factor: 3.835

3.  Implementation of a study to examine the persistence of Ebola virus in the body fluids of Ebola virus disease survivors in Sierra Leone: Methodology and lessons learned.

Authors:  Gibrilla Fadlu Deen; Suzanna L R McDonald; Jaclyn E Marrinan; Foday R Sesay; Elizabeth Ervin; Anna E Thorson; Wenbo Xu; Ute Ströher; Patricia Ongpin; Neetu Abad; Archchun Ariyarajah; Tasneem Malik; Hongtu Liu; Christine Ross; Kara N Durski; Philippe Gaillard; Oliver Morgan; Pierre Formenty; Barbara Knust; Nathalie Broutet; Foday Sahr
Journal:  PLoS Negl Trop Dis       Date:  2017-09-11

4.  VSITA, an Improved Approach of Target Amplification in the Identification of Viral Pathogens.

Authors:  Yi Zhang; Chen Zhang; Bo Li; Yang Li; Xiao Zhou He; Acher Li; Wei Wu; Su Xia Duan; Fang Zhou Qiu; Ji Wang; Xin Xin Shen; Meng Jie Yang; De Xin Li; Xue Jun Ma
Journal:  Biomed Environ Sci       Date:  2018-04       Impact factor: 3.118

  4 in total

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