Literature DB >> 2746964

[Genetic variants of the complement components and HLA-antigens associated in patients with psoriasis vulgaris in Japanese].

H Nakagawa, K Tokunaga, G Dewald, K Omoto, Y Ishibashi, K Matsuki, T Juji.   

Abstract

Genetic polymorphisms of the serum complement components (C2, C4, C6, and C7) and HLA-antigens were studied in Japanese patients with psoriasis vulgaris. Among these complement components, positive associations with C4A4 and C4B2 were obtained. In addition to the previously reported haplotypes HLA-Cw6-B13 and Cw6-Bw57-DR7, the extended haplotype HLA-Cw11-Bw46-C4A4. 4B2-BFS-C2C-DRw8 may be a high risk haplotype in Japanese patients with psoriasis vulgaris.

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Year:  1989        PMID： 2746964

Source DB:  PubMed          Journal:  Nihon Hifuka Gakkai Zasshi        ISSN： 0021-499X


  2 in total

1.  Correlation between HLA-A2-Bw46-DRw8 haplotype and increased levels of complement components (C4 and C4a) in patients with psoriatic arthritis.

Authors:  M Muto; M Mashimo; K Urabe; T Suzuki; T Sasazuki
Journal:  Arch Dermatol Res       Date:  1991       Impact factor: 3.017

2.  Hla-a and hla-B alleles associated in psoriasis patients from mumbai, Western India.

Authors:  Shankarkumar Umapathy; Aruna Pawar; R Mitra; D Khuperkar; J P Devaraj; K Ghosh; U Khopkar
Journal:  Indian J Dermatol       Date:  2011 Sep-Oct       Impact factor: 1.494
  2 in total

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