Dong Soo Yu1, Hyun Jee Kim1, Yong Gyu Park2, Jung Min Bae1, Jin-Wou Kim1, Young Bok Lee1. 1. a Department of Dermatology , College of Medicine, The Catholic University of Korea , Seoul , Korea. 2. b Department of Biostatistics , College of Medicine, The Catholic University of Korea , Seoul , Korea.
Abstract
BACKGROUND: There have been few studies regarding the results of the Korean standard patch test. OBJECTIVES: The purpose of this study was to analyze the type and frequency of common contact allergens in Korea and to compare the results with those of previous reports. METHODS: From June 2009 to June 2014, 330 patients with suspected allergic contact dermatitis who visited our clinic were tested using the Korean standard patch test. RESULTS: The highest sensitization rate was found for nickel sulfate (47.58%). There was a significant gender difference in the prevalence of sensitization to nickel sulfate (OR = 2.41, p = .0004) and wool alcohol (OR = 2.85, p = .0358). Higher sensitization to nickel sulfate (OR = 1.18, p = .0159), 4-phenylenediamine (OR = 1.23, p= .003), tixocortol-21-pivalte (OR 1.48, p = .0212) and lower sensitization to thimerosal (OR = 0.77, p = .0023) were associated with increasing age. Patients with allergic contact dermatitis on the scalp had a significantly higher risk of sensitization to 4-phenylenediamine (OR = 3.07, p = .0013). Patients with allergic contact dermatitis on the hands had significantly higher risks of sensitization to wool alcohol (OR = 3.44, p = .0083), formaldehyde (OR = 2.52, p = .0178), and colophony (OR = 2.05, p = .0499). CONCLUSIONS: These results demonstrate trends in patch test results in Korea and the basis for the presumption of the route of allergen exposure.
BACKGROUND: There have been few studies regarding the results of the Korean standard patch test. OBJECTIVES: The purpose of this study was to analyze the type and frequency of common contact allergens in Korea and to compare the results with those of previous reports. METHODS: From June 2009 to June 2014, 330 patients with suspected allergic contact dermatitis who visited our clinic were tested using the Korean standard patch test. RESULTS: The highest sensitization rate was found for nickel sulfate (47.58%). There was a significant gender difference in the prevalence of sensitization to nickel sulfate (OR = 2.41, p = .0004) and wool alcohol (OR = 2.85, p = .0358). Higher sensitization to nickel sulfate (OR = 1.18, p = .0159), 4-phenylenediamine (OR = 1.23, p= .003), tixocortol-21-pivalte (OR 1.48, p = .0212) and lower sensitization to thimerosal (OR = 0.77, p = .0023) were associated with increasing age. Patients with allergic contact dermatitis on the scalp had a significantly higher risk of sensitization to 4-phenylenediamine (OR = 3.07, p = .0013). Patients with allergic contact dermatitis on the hands had significantly higher risks of sensitization to wool alcohol (OR = 3.44, p = .0083), formaldehyde (OR = 2.52, p = .0178), and colophony (OR = 2.05, p = .0499). CONCLUSIONS: These results demonstrate trends in patch test results in Korea and the basis for the presumption of the route of allergen exposure.
Entities:
Keywords:
Allergen; allergic contact dermatitis; patch test
Authors: Seok Young Kang; Bo Young Chung; Jin Cheol Kim; Chun Wook Park; Hye One Kim Journal: J Am Acad Dermatol Date: 2021-06-14 Impact factor: 11.527
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