Literature DB >> 27467951

Regulatory B lymphocyte functions should be considered in chronic lymphocytic leukemia.

Audrey Mohr1, Yves Renaudineau2, Cristina Bagacean2, Jacques-Olivier Pers1, Christophe Jamin2, Anne Bordron1.   

Abstract

Chronic lymphocytic leukemia (CLL) is characterized by an abnormal expansion of mature B cells in the bone marrow and their accumulation in blood and secondary lymphoid organs. Tumor CLL cells share expression of various surface molecules with many subsets of B cells and have several common characteristics with regulatory B cells (B regs). However, the identification of B regs and their role in CLL remain elusive. The aim of this review is to summarize recent works regarding the regulatory and phenotypic characteristic of B regs and their associated effects on the immune system. It is also meant to highlight their potential importance with regards to the immunotherapeutic response.

Entities:  

Keywords:  B lymphocytes; CLL; immunotherapy; regulatory B cell

Year:  2016        PMID： 27467951      PMCID： PMC4910744          DOI： 10.1080/2162402X.2015.1132977

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  104 in total

Review 1.  NKT cells: what's in a name?

Authors:  Dale I Godfrey; H Robson MacDonald; Mitchell Kronenberg; Mark J Smyth; Luc Van Kaer
Journal:  Nat Rev Immunol       Date:  2004-03       Impact factor: 53.106

2.  Regulatory dendritic cells program B cells to differentiate into CD19hiFcγIIbhi regulatory B cells through IFN-β and CD40L.

Authors:  Li Qian; Cheng Qian; Yongjian Chen; Yi Bai; Yan Bao; Liwei Lu; Xuetao Cao
Journal:  Blood       Date:  2012-06-12       Impact factor: 22.113

3.  High functional CD70 expression on α-type 1-polarized dendritic cells from patients with chronic lymphocytic leukaemia.

Authors:  K Junevik; O Werlenius; L Fogelstrand; A Karlsson-Parra; P-O Andersson
Journal:  Scand J Immunol       Date:  2014-06       Impact factor: 3.487

Review 4.  Raising the NKT cell family.

Authors:  Dale I Godfrey; Sanda Stankovic; Alan G Baxter
Journal:  Nat Immunol       Date:  2010-02-07       Impact factor: 25.606

5.  The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting.

Authors:  T Vaisitti; V Audrito; S Serra; R Buonincontri; G Sociali; E Mannino; A Pagnani; A Zucchetto; E Tissino; C Vitale; M Coscia; C Usai; C Pepper; V Gattei; S Bruzzone; S Deaglio
Journal:  Leukemia       Date:  2014-07-03       Impact factor: 11.528

6.  Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine.

Authors:  Marc Beyer; Matthias Kochanek; Kamruz Darabi; Alexey Popov; Markus Jensen; Elmar Endl; Percy A Knolle; Roman K Thomas; Michael von Bergwelt-Baildon; Svenja Debey; Michael Hallek; Joachim L Schultze
Journal:  Blood       Date:  2005-05-24       Impact factor: 22.113

7.  Tolerant Kidney Transplant Patients Produce B Cells with Regulatory Properties.

Authors:  Mélanie Chesneau; Laure Michel; Emilie Dugast; Alexis Chenouard; Daniel Baron; Annaïck Pallier; Justine Durand; Faouzi Braza; Pierrick Guerif; David-Axel Laplaud; Jean-Paul Soulillou; Magali Giral; Nicolas Degauque; Elise Chiffoleau; Sophie Brouard
Journal:  J Am Soc Nephrol       Date:  2015-02-02       Impact factor: 10.121

8.  CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients.

Authors:  Paul A Blair; Lina Yassin Noreña; Fabian Flores-Borja; David J Rawlings; David A Isenberg; Michael R Ehrenstein; Claudia Mauri
Journal:  Immunity       Date:  2010-01-14       Impact factor: 31.745

9.  The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia.

Authors:  Davide Brusa; Sara Serra; Marta Coscia; Davide Rossi; Giovanni D'Arena; Luca Laurenti; Ozren Jaksic; Giorgio Fedele; Giorgio Inghirami; Gianluca Gaidano; Fabio Malavasi; Silvia Deaglio
Journal:  Haematologica       Date:  2013-01-08       Impact factor: 9.941

Review 10.  The roles of regulatory B cells in cancer.

Authors:  Yan He; Hongyan Qian; Yuan Liu; Lihua Duan; Yan Li; Guixiu Shi
Journal:  J Immunol Res       Date:  2014-06-02       Impact factor: 4.818
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  7 in total

1.  Memory B Cells and Response to Abatacept in Rheumatoid Arthritis.

Authors:  Pierre Gazeau; Guillermo Carvajal Alegria; Valérie Devauchelle-Pensec; Christophe Jamin; Julie Lemerle; Boutahar Bendaoud; Wesley H Brooks; Alain Saraux; Divi Cornec; Yves Renaudineau
Journal:  Clin Rev Allergy Immunol       Date:  2017-10       Impact factor: 8.667

2.  The regulatory capacity of B cells directs the aggressiveness of CLL.

Authors:  Audrey Mohr; Marie Cumin; Cristina Bagacean; Pierre Pochard; Christelle Le Dantec; Sophie Hillion; Yves Renaudineau; Christian Berthou; Adrian Tempescul; Hussam Saad; Jacques-Olivier Pers; Anne Bordron; Christophe Jamin
Journal:  Oncoimmunology       Date:  2018-12-12       Impact factor: 8.110

3.  Targeting CD38 is lethal to Breg-like chronic lymphocytic leukemia cells and Tregs, but restores CD8+ T-cell responses.

Authors:  Alak Manna; Timothy Kellett; Sonikpreet Aulakh; Laura J Lewis-Tuffin; Navnita Dutta; Keith Knutson; Eduardo Chini; Javier Pinilla-Ibarz; Nicole Lamanna; Rami Manochakian; Fabio Malavasi; Taimur Sher; Asher A Chanan-Khan; Sikander Ailawadhi; Aneel Paulus
Journal:  Blood Adv       Date:  2020-05-26

4.  Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cells.

Authors:  Barry D Hock; Sean A MacPherson; Judith L McKenzie
Journal:  PLoS One       Date:  2017-03-03       Impact factor: 3.240

5.  MiR-15a/16-1 deficiency induces IL-10-producing CD19+ TIM-1+ cells in tumor microenvironment.

Authors:  Xiaoqin Jia; Hao Liu; Chong Xu; Sen Han; Yating Shen; Xin Miao; Xiangyu Hu; Zhijie Lin; Li Qian; Zhengbing Wang; Weijuan Gong
Journal:  J Cell Mol Med       Date:  2018-11-23       Impact factor: 5.310

6.  The Role of Alpha 2 Macroglobulin in IgG-Aggregation and Chronic Activation of the Complement System in Patients With Chronic Lymphocytic Leukemia.

Authors:  Naseba Naseraldeen; Regina Michelis; Masad Barhoum; Judith Chezar; Tamar Tadmor; Ariel Aviv; Lev Shvidel; Adi Litmanovich; Mona Shehadeh; Galia Stemer; Ety Shaoul; Andrei Braester
Journal:  Front Immunol       Date:  2021-02-11       Impact factor: 7.561

Review 7.  Metabolic Program of Regulatory B Lymphocytes and Influence in the Control of Malignant and Autoimmune Situations.

Authors:  Cristian Iperi; Anne Bordron; Maryvonne Dueymes; Jacques-Olivier Pers; Christophe Jamin
Journal:  Front Immunol       Date:  2021-09-28       Impact factor: 7.561
  7 in total

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