Tze Wei Chng1, Jonathan Y H Lee2, C Soon Lee3, HuiHua Li4, Min-Han Tan5, Puay Hoon Tan6. 1. Department of Anatomical Pathology, Singapore General Hospital, Singapore. 2. School of Health and Science, Western Sydney University, Western Sydney, Australia. 3. Discipline of Pathology, School of Medicine, Western Sydney University; Cancer Pathology, Bosch Institute, University of Sydney; Ingham Institute for Applied Medical Research, and South Western Sydney Clinical School, UNSW, Liverpool, New South Wales, Australia. 4. Division of Medicine, Singapore General Hospital, Singapore. 5. Division of Biodevices and Diagnostics, Institute of Bioengineering and Nanotechnology, Singapore. 6. Division of Pathology, Singapore General Hospital, Singapore.
Abstract
AIM: To validate the utility of the Singapore nomogram for outcome prediction in breast phyllodes tumours. METHODS: Histological parameters, surgical margin status and clinical follow-up data of 34 women diagnosed with phyllodes tumours were analysed. Biostatistics modelling was performed, and the concordance between predicted and observed survivals was calculated. RESULTS: Women with a high nomogram score had an increased risk of developing relapse, which was predicted using the parameters defined by the Singapore nomogram. CONCLUSIONS: The Singapore nomogram is useful in predicting outcome in breast phyllodes tumours when applied to an Australian cohort of 34 women. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
AIM: To validate the utility of the Singapore nomogram for outcome prediction in breast phyllodes tumours. METHODS: Histological parameters, surgical margin status and clinical follow-up data of 34 women diagnosed with phyllodestumours were analysed. Biostatistics modelling was performed, and the concordance between predicted and observed survivals was calculated. RESULTS:Women with a high nomogram score had an increased risk of developing relapse, which was predicted using the parameters defined by the Singapore nomogram. CONCLUSIONS: The Singapore nomogram is useful in predicting outcome in breast phyllodes tumours when applied to an Australian cohort of 34 women. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
Entities:
Keywords:
BREAST PATHOLOGY; DIAGNOSTICS; NEOPLASMS