Literature DB >> 27464739

[Electrolyte disturbances in geriatric patients with focus on hyponatremia].

F Grundmann1.   

Abstract

Disturbances of water and electrolyte balance are commonly encountered in older patients due to a multitude of physiological changes and preexisting morbidities with hyponatremia being the most common disorder. Even mild chronic hyponatremia can lead to cognitive deficits and gait instability and is associated with an increased rate of falls and fractures. Additionally, experimental and epidemiological data suggest that hyponatremia promotes bone resorption and therefore increases the risk of osteoporosis. Furthermore, osteoporosis and sarcopenia can be stimulated by hypomagnesemia. Hypernatremia often only results in unspecific symptoms but the condition is associated with a clearly increased mortality. As electrolyte disturbances have a high prevalence in the geriatric population and can contribute to geriatric syndromes and frailty, relevant electrolyte alterations should be excluded in all geriatric patients, in particular after a change in medication schedules.

Entities:  

Keywords:  Aging; Hyponatremia; Osmolarity; Water; Water electrolyte imbalance

Mesh:

Year:  2016        PMID: 27464739     DOI: 10.1007/s00391-016-1117-y

Source DB:  PubMed          Journal:  Z Gerontol Geriatr        ISSN: 0948-6704            Impact factor:   1.281


  31 in total

Review 1.  Fluid and electrolytes in the aged.

Authors:  Andrew E Luckey; Cyrus J Parsa
Journal:  Arch Surg       Date:  2003-10

Review 2.  Brain volume regulation in response to changes in osmolality.

Authors:  J G Verbalis
Journal:  Neuroscience       Date:  2010-04-24       Impact factor: 3.590

Review 3.  Prevalence of hyponatremia on geriatric wards compared to other settings over four decades: a systematic review.

Authors:  Cyndie K Mannesse; Ariël M Vondeling; Rob J van Marum; Wouter W van Solinge; Toine C G Egberts; Paul A F Jansen
Journal:  Ageing Res Rev       Date:  2012-05-12       Impact factor: 10.895

Review 4.  Association Between Hyponatremia, Osteoporosis, and Fracture: A Systematic Review and Meta-analysis.

Authors:  Sikarin Upala; Anawin Sanguankeo
Journal:  J Clin Endocrinol Metab       Date:  2016-02-25       Impact factor: 5.958

5.  The effect of aging on intestinal absorption and status of calcium, magnesium, zinc, and copper in rats: a stable isotope study.

Authors:  Charles Coudray; Christine Feillet-Coudray; Mathieu Rambeau; Jean Claude Tressol; Elyett Gueux; Andrzej Mazur; Yves Rayssiguier
Journal:  J Trace Elem Med Biol       Date:  2005-12-20       Impact factor: 3.849

6.  Mild hyponatremia as a risk factor for fractures: the Rotterdam Study.

Authors:  Ewout J Hoorn; Fernando Rivadeneira; Joyce B J van Meurs; Gijsbertus Ziere; Bruno H Ch Stricker; Albert Hofman; Huibert A P Pols; Robert Zietse; André G Uitterlinden; M Carola Zillikens
Journal:  J Bone Miner Res       Date:  2011-08       Impact factor: 6.741

7.  Hypernatremia in elderly patients. A heterogeneous, morbid, and iatrogenic entity.

Authors:  N A Snyder; D W Feigal; A I Arieff
Journal:  Ann Intern Med       Date:  1987-09       Impact factor: 25.391

8.  Hyponatremia independent of osteoporosis is associated with fracture occurrence.

Authors:  Sinead Kinsella; Sarah Moran; Miriam O Sullivan; Michael G M Molloy; Joseph A Eustace
Journal:  Clin J Am Soc Nephrol       Date:  2010-01-07       Impact factor: 8.237

9.  Hypernatremia in the elderly.

Authors:  Olufemi Adeleye; Marquetta Faulkner; Tolulola Adeola; Gerard ShuTangyie
Journal:  J Natl Med Assoc       Date:  2002-08       Impact factor: 1.798

10.  Two distinct modes of hypoosmotic medium-induced release of excitatory amino acids and taurine in the rat brain in vivo.

Authors:  Renée E Haskew-Layton; Alena Rudkouskaya; Yiqiang Jin; Paul J Feustel; Harold K Kimelberg; Alexander A Mongin
Journal:  PLoS One       Date:  2008-10-28       Impact factor: 3.240

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  2 in total

1.  Hyponatremia in elderly patients with fragility fractures of the proximal femur: a cross-sectional study.

Authors:  Aída Fernanda Batista Rocha; Marcus Villander Barros De Oliveira Sá; Ubirace Fernando Elihimas Junior
Journal:  J Bras Nefrol       Date:  2019 Oct-Dec

2.  Hyponatremia in the frail.

Authors:  Nikolaos D Karakousis; Nikolaos A Kostakopoulos
Journal:  J Frailty Sarcopenia Falls       Date:  2021-12-01
  2 in total

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